在微流控通道中通过花青素-3的硝基衍生物（NCy3）对亚硫酸氢盐进行分析。
Analysis of Bisulfite Via a Nitro Derivative of Cyanine-3 (NCy3) in the Microfluidic Channel.
作者信息
Houtwed Haley A, Xie Meng, Ahmad Aatiya, Masters Cody D, Davison Melissa M, Kounovsky-Shafer Kristy, Cao Haishi
机构信息
Department of Chemistry, University of Nebraska-Kearney, Kearney, NE, 68849, USA.
出版信息
J Fluoresc. 2019 May;29(3):523-529. doi: 10.1007/s10895-019-02394-0. Epub 2019 May 28.
Abstract
NCy3, a derivative of Cyanine 3 with a nitro substituent, showed a high reactivity to bisulfite in aqueous media, instantly leading to ratiometric change of absorption spectra and significant fluorescence quenching. Applied in the microfluidic channel, NCy3 functionalize as a sensitive approach for quantitative detection of bisulfite, particularly for samples with a small volume.
摘要
NCy3是一种带有硝基取代基的花菁3衍生物，在水性介质中对亚硫酸氢盐表现出高反应活性，能立即导致吸收光谱的比例变化和显著的荧光猝灭。应用于微流控通道时，NCy3可作为一种灵敏的方法用于定量检测亚硫酸氢盐，尤其适用于小体积样品。
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