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肥胖儿童的心房电机械延迟评估。

Evaluation of Atrial Electromechanical Delay in Children with Obesity.

机构信息

Sutcu Imam University, Department of Pediatric Endocrinology, 46100 Kahramanmaras, Turkey.

Sutcu Imam University, Department of Pediatrics, 46040 Kahramanmaras, Turkey.

出版信息

Medicina (Kaunas). 2019 May 30;55(6):228. doi: 10.3390/medicina55060228.

Abstract

UNLABELLED

: Childhood obesity is one of the worldwide health problems with an increasing prevalence and accompanied by severe morbidity and mortality. It is a serious predisposing risk factor especially for the development of cardiovascular diseases and arrhythmias. Electromechanical delay (EMD) is known to be a predictor for the development of atrial fibrillation (AF). Our study aims to investigate whether EMD, which is a predictor of AF, prolongs in obese children or not.

MATERIAL AND METHODS

The study included 59 obese patients aged between 8-18 years and 38 healthy patients as the control group with a similar age and gender. All the individuals underwent transthoracic echo and tissue Doppler echocardiography. Systolic and diastolic left ventricular (LV) functions, inter- and intra-atrial electromechanical delay were measured by tissue Doppler imaging (TDI) and conventional echocardiography.

RESULTS

Obese patients had significantly lengthened P-wave on surface ECG to the beginning of the late diastolic wave (PA) lateral, PA septum, intra- and inter-atrial electromechanical delays when compared with the control group ( 0.001, = 0.001, < 0.001 and < 0.001, respectively) Inter-atrial EMD and intra-atrial EMD correlated positively with body mass index (BMI) values ( = 0.484, < 0.001 and = 0.376, = 0.001; respectively) BMI was significantly related with inter-atrial EMD ( = 0.473, < 0.001) However, there was no relationship between inter-atrial EMD and serum glucose and platelet count.

CONCLUSION

In our study, we declared that electromechanical delay was increased in obese children when compared to the control group and intra- and inter-atrial electromechanical delay was in correlation with body mass index. Furthermore, we discovered that BMI is an independent predictor of the inter-atrial EMD in obese children.

摘要

目的

研究电机械延迟(EMD)是否会在肥胖儿童中延长,已知 EMD 是心房颤动(AF)发生的预测因素。

材料和方法

研究纳入了 59 名年龄在 8-18 岁之间的肥胖患者和 38 名年龄和性别相似的健康患者作为对照组。所有患者均接受经胸超声心动图和组织多普勒超声心动图检查。采用组织多普勒成像(TDI)和常规超声心动图测量左心室(LV)收缩和舒张功能、房间隔和室内隔的电机械延迟。

结果

与对照组相比,肥胖患者体表心电图 P 波至晚期舒张波(PA)起始的时间明显延长(PA)外侧、PA 间隔、房间隔和室内隔的电机械延迟( 0.001, = 0.001, < 0.001 和 < 0.001,分别)。房间隔 EMD 和室内隔 EMD 与体重指数(BMI)值呈正相关( = 0.484, < 0.001 和 = 0.376, = 0.001;分别)。BMI 与房间隔 EMD 显著相关( = 0.473, < 0.001)。然而,房间隔 EMD 与血清葡萄糖和血小板计数之间没有关系。

结论

与对照组相比,肥胖儿童的电机械延迟增加,且房间隔和室内隔的电机械延迟与体重指数相关。此外,我们发现 BMI 是肥胖儿童房间隔 EMD 的独立预测因子。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4dcb/6630771/fe74d41f3b27/medicina-55-00228-g001.jpg

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