Sutcu Imam University, Department of Pediatric Endocrinology, 46100 Kahramanmaras, Turkey.
Sutcu Imam University, Department of Pediatrics, 46040 Kahramanmaras, Turkey.
Medicina (Kaunas). 2019 May 30;55(6):228. doi: 10.3390/medicina55060228.
: Childhood obesity is one of the worldwide health problems with an increasing prevalence and accompanied by severe morbidity and mortality. It is a serious predisposing risk factor especially for the development of cardiovascular diseases and arrhythmias. Electromechanical delay (EMD) is known to be a predictor for the development of atrial fibrillation (AF). Our study aims to investigate whether EMD, which is a predictor of AF, prolongs in obese children or not.
The study included 59 obese patients aged between 8-18 years and 38 healthy patients as the control group with a similar age and gender. All the individuals underwent transthoracic echo and tissue Doppler echocardiography. Systolic and diastolic left ventricular (LV) functions, inter- and intra-atrial electromechanical delay were measured by tissue Doppler imaging (TDI) and conventional echocardiography.
Obese patients had significantly lengthened P-wave on surface ECG to the beginning of the late diastolic wave (PA) lateral, PA septum, intra- and inter-atrial electromechanical delays when compared with the control group ( 0.001, = 0.001, < 0.001 and < 0.001, respectively) Inter-atrial EMD and intra-atrial EMD correlated positively with body mass index (BMI) values ( = 0.484, < 0.001 and = 0.376, = 0.001; respectively) BMI was significantly related with inter-atrial EMD ( = 0.473, < 0.001) However, there was no relationship between inter-atrial EMD and serum glucose and platelet count.
In our study, we declared that electromechanical delay was increased in obese children when compared to the control group and intra- and inter-atrial electromechanical delay was in correlation with body mass index. Furthermore, we discovered that BMI is an independent predictor of the inter-atrial EMD in obese children.
研究电机械延迟（EMD）是否会在肥胖儿童中延长，已知 EMD 是心房颤动（AF）发生的预测因素。
研究纳入了 59 名年龄在 8-18 岁之间的肥胖患者和 38 名年龄和性别相似的健康患者作为对照组。所有患者均接受经胸超声心动图和组织多普勒超声心动图检查。采用组织多普勒成像（TDI）和常规超声心动图测量左心室（LV）收缩和舒张功能、房间隔和室内隔的电机械延迟。
与对照组相比，肥胖患者体表心电图 P 波至晚期舒张波（PA）起始的时间明显延长（PA）外侧、PA 间隔、房间隔和室内隔的电机械延迟（ 0.001， = 0.001， < 0.001 和 < 0.001，分别）。房间隔 EMD 和室内隔 EMD 与体重指数（BMI）值呈正相关（ = 0.484， < 0.001 和 = 0.376， = 0.001；分别）。BMI 与房间隔 EMD 显著相关（ = 0.473， < 0.001）。然而，房间隔 EMD 与血清葡萄糖和血小板计数之间没有关系。
与对照组相比，肥胖儿童的电机械延迟增加，且房间隔和室内隔的电机械延迟与体重指数相关。此外，我们发现 BMI 是肥胖儿童房间隔 EMD 的独立预测因子。
