Department of Urology, University of California, San Francisco, San Francisco, CA, USA.
Department of Biostatistics and Epidemiology, University of California, San Francisco, San Francisco, CA, USA.
J Sex Med. 2019 Aug;16(8):1236-1245. doi: 10.1016/j.jsxm.2019.04.020. Epub 2019 May 31.
BACKGROUND: Sexual dysfunction is common among adults and takes a toll on quality of life for both men and women. AIM: To determine whether higher levels of weekly cardiovascular exercise are protective against self-reported sexual dysfunction among men and women. METHODS: We conducted an international online, cross-sectional survey of physically active men and women between April and December 2016, assessing exercise activity categorized into sextiles of weekly metabolic equivalent-hours. Odds ratios (ORs) of sexual dysfunction for each activity sextile compared with the lowest sextile were calculated using multivariable logistic regression, controlling for age, body mass index, diabetes mellitus, tobacco/alcohol use, sport, and marital status. MAIN OUTCOME MEASURES: Female sexual dysfunction was defined as a score ≤26.55 on the Female Sexual Function Inventory and erectile dysfunction (ED) was defined as a score ≤21 on the Sexual Health Inventory for Men. RESULTS: 3,906 men and 2,264 women (median age 41-45 and 31-35 years, respectively) met the inclusion criteria for the study. Men in sextiles 2-6 had reduced odds of ED compared with the reference sextile in adjusted analysis (P = .03), with an OR of 0.77 (95% CI = 0.61-0.97) for sextile 4 and 0.78 (95% CI = 0.62-0.99) for sextile 6, both statistically significant. Women in higher sextiles had a reduced adjusted OR of female sexual dysfunction (P = .02), which was significant in sextile 4 (OR = 0.70; 95% CI = 0.51-0.96). A similar pattern held true for orgasm dissatisfaction (P < .01) and arousal difficulty (P < .01) among women, with sextiles 4-6 reaching statistical significance in both. CLINICAL IMPLICATIONS: Men and women at risk for sexual dysfunction regardless of physical activity level may benefit by exercising more rigorously. STRENGTHS & LIMITATIONS: Strengths include using a large international sample of participants with a wide range of physical activity levels. Limitations include the cross-sectional design, and results should be interpreted in context of the study population of physically active adults. CONCLUSION: Higher cardiovascular exercise levels in physically active adults are inversely associated with ED by self-report in men and protective against female sexual dysfunction in women. Fergus KB, Gaither TW, Baradaran N, et al. Exercise Improves Self-Reported Sexual Function Among Physically Active Adults. J Sex Med 2019;16:1236-1245.
背景：性障碍在成年人中很常见，会降低男性和女性的生活质量。
目的：确定每周进行更高水平的心血管锻炼是否能预防男性和女性自我报告的性障碍。
方法：我们于 2016 年 4 月至 12 月期间，对身体活跃的男性和女性进行了一项国际性的在线横断面调查，评估了每周代谢当量小时数分为六等分的运动活动。使用多变量逻辑回归计算每个活动六等分与最低六等分相比的性障碍比值比（OR），并控制年龄、体重指数、糖尿病、烟酒使用、运动和婚姻状况。
主要观察指标：女性性障碍定义为女性性功能问卷评分≤26.55，男性勃起功能障碍定义为男性性功能健康问卷评分≤21。
结果：3906 名男性和 2264 名女性（中位数年龄分别为 41-45 岁和 31-35 岁）符合研究纳入标准。调整分析后，男性第 2-6 六等分的 ED 发生几率低于参考六等分（P=0.03），第 4 六等分的 OR 为 0.77（95%CI 0.61-0.97），第 6 六等分的 OR 为 0.78（95%CI 0.62-0.99），均有统计学意义。较高六等分的女性性障碍调整后 OR 降低（P=0.02），第 4 六等分有统计学意义（OR=0.70；95%CI 0.51-0.96）。女性的性高潮不满意（P<0.01）和性欲困难（P<0.01）也呈现出类似的模式，第 4-6 六等分均有统计学意义。
临床意义：无论体力活动水平如何，有性障碍风险的男性和女性可能通过更严格的锻炼从中受益。
局限性：本研究的优势包括使用了具有广泛体力活动水平的大型国际参与者样本。局限性包括横断面设计，结果应结合身体活跃成年人的研究人群进行解释。
结论：体力活动活跃的成年人中，心血管锻炼水平越高，男性勃起功能障碍的自我报告发生率越低，女性的性障碍发生率越低。
J Sex Med. 2019-5-31
Int J Sex Health. 2022-12-1
Int J Sex Health. 2022-1-25
Int J Sex Health. 2021-9-25
Indian J Psychiatry. 2024-1
Healthcare (Basel). 2023-12-29
Am J Lifestyle Med. 2022-5-16
Zotero 插件