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Fibrinogen-like protein 2: a potential molecular target for glioblastoma treatment.

作者信息

Patel Rajan, Traylor Jeffrey I, Latha Khatri, Heimberger Amy B, Li Shulin, Rao Ganesh

机构信息

a Department of Neurosurgery , The University of Texas MD Anderson Cancer Center , Houston , TX , USA.

b Department of Pediatrics-Research , The University of Texas MD Anderson Cancer Center , Houston , TX , USA.

出版信息

Expert Opin Ther Targets. 2019 Aug;23(8):647-649. doi: 10.1080/14728222.2019.1628220. Epub 2019 Jun 5.

Abstract
摘要

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本文引用的文献

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FGL2 promotes tumor progression in the CNS by suppressing CD103 dendritic cell differentiation.
Nat Commun. 2019 Jan 25;10(1):448. doi: 10.1038/s41467-018-08271-x.
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Combined Nivolumab and Ipilimumab in Melanoma Metastatic to the Brain.
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The Role of Fibrinogen-Like Protein 2 on Immunosuppression and Malignant Progression in Glioma.
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FGL2 as a Multimodality Regulator of Tumor-Mediated Immune Suppression and Therapeutic Target in Gliomas.
J Natl Cancer Inst. 2015 May 13;107(8). doi: 10.1093/jnci/djv137. Print 2015 Aug.
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Dissecting the tumor myeloid compartment reveals rare activating antigen-presenting cells critical for T cell immunity.
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