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Managing drug-drug interactions with boceprevir and telaprevir.

作者信息

Rangnekar Amol S, Fontana Robert J

机构信息

Division of Gastroenterology, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, MI.

出版信息

Clin Liver Dis (Hoboken). 2012 Apr 26;1(2):36-40. doi: 10.1002/cld.10. eCollection 2012 Apr.

Abstract
摘要

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本文引用的文献

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Effect of the hepatitis C virus protease inhibitor telaprevir on the pharmacokinetics of amlodipine and atorvastatin.
Antimicrob Agents Chemother. 2011 Oct;55(10):4569-74. doi: 10.1128/AAC.00653-11. Epub 2011 Aug 8.
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Effect of telaprevir on the pharmacokinetics of cyclosporine and tacrolimus.
Hepatology. 2011 Jul;54(1):20-7. doi: 10.1002/hep.24443.
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Mechanism-based inhibition of cytochrome P450 3A4 by therapeutic drugs.
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Pharmacogenomics--drug disposition, drug targets, and side effects.
N Engl J Med. 2003 Feb 6;348(6):538-49. doi: 10.1056/NEJMra020526.
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P450 gene induction by structurally diverse xenochemicals: central role of nuclear receptors CAR, PXR, and PPAR.
Arch Biochem Biophys. 1999 Sep 1;369(1):11-23. doi: 10.1006/abbi.1999.1351.
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Effects of a chargrilled meat diet on expression of CYP3A, CYP1A, and P-glycoprotein levels in healthy volunteers.
Gastroenterology. 1999 Jul;117(1):89-98. doi: 10.1016/s0016-5085(99)70554-8.

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