Jang Gi Young, Ha Kee Soo
Department of Pediatrics, Korea University Hospital, Ansan, Korea.
Korean Circ J. 2019 Oct;49(10):932-942. doi: 10.4070/kcj.2019.0067. Epub 2019 May 29.
Vascular stenosis after surgical repair frequently occurs in congenital heart disease. Although conventional balloon dilation is a useful option for stenotic lesions, restenosis may occur. Consequently, balloon expandable stents have been used; however, there are a limited number of balloon expandable stents in our country. Here, we report the early and intermediate-term outcomes of self-expandable stents in vascular stenosis of moderate to large-sized vessels in congenital heart disease.
Twelve self-expandable stents were implanted in 9 patients between February 2012 and January 2019. The median age and weight were 12 years (range, 4-39 years) and 38 kg (range, 19-69 kg), respectively. The patients were followed-up for a median duration of 43 months (range, 1-83 months) after stent implantation.
Nine self-expandable stents were implanted in the pulmonary artery, 2 stents in the right ventricle to the pulmonary artery conduit, and 1 stent in the coarctation. The narrowest diameter of the stented vessel increased from 5.7±3.2 mm to 12.6±3.4 mm (p<0.05). The mean pressure gradient across the stenotic lesion decreased from 23.0±28.2 mmHg to 3.2±3.6 mmHg (p<0.05). Distal migration of the stent occurred in 1 patient, and significant neointimal ingrowth was noted in 1 patient.
The self-expandable stent may be a useful option to relieve vascular stenosis in moderate to large-sized vessels with acceptable intermediate-term outcomes.
先天性心脏病手术修复后血管狭窄经常发生。尽管传统球囊扩张术对狭窄病变是一种有用的选择,但可能会发生再狭窄。因此,已经使用了球囊扩张支架;然而,我国球囊扩张支架的数量有限。在此,我们报告了自膨胀支架在先天性心脏病中、大型血管狭窄中的早期和中期结果。
2012年2月至2019年1月期间,9例患者植入了12个自膨胀支架。中位年龄和体重分别为12岁(范围4 - 39岁)和38 kg(范围19 - 69 kg)。支架植入后,患者的中位随访时间为43个月(范围1 - 83个月)。
9个自膨胀支架植入肺动脉,2个支架植入右心室至肺动脉管道,1个支架植入缩窄部位。置入支架血管的最窄直径从5.7±3.2 mm增加到12.6±3.4 mm(p<0.05)。狭窄病变两端的平均压力阶差从23.0±28.2 mmHg降至3.2±3.6 mmHg(p<0.05)。1例患者发生支架远端移位,1例患者出现明显的新生内膜增生。
自膨胀支架可能是缓解中、大型血管狭窄的一种有用选择,中期结果可接受。