Department of Veterinary Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Abuja, Abuja, Nigeria.
Department of Veterinary Biochemistry and Physiology, Faculty of Veterinary Medicine, University of Abuja, Abuja, Nigeria.
Drug Chem Toxicol. 2021 Sep;44(5):518-523. doi: 10.1080/01480545.2019.1621334. Epub 2019 Jun 14.
Cowpea () is a source of plant protein that is widely consumed by the Nigerian populace. The aim of the study was to evaluate the health risk of heavy metals in two cowpea types sold in Gwagwalada Market, Nigeria. The concentrations of five heavy metals nickel (Ni), cadmium (Cd), manganese (Mn), cobalt (Co), and chromium (Cr) were assessed in the cowpea types. Samples of each type were randomly purchased and the heavy metal concentrations (mg/kg) were analyzed with an atomic absorption spectrophotometer. The concentrations of the heavy metals in mg/kg dry weight of the brown type were as follows: Ni (2.45 ± 0.87), Cd (0.26 ± 0.10), Mn (9.11 ± 1.80), and Co (1.67 ± 0.20), while the concentrations for the white type were: Ni (4.55 ± 1.21), Cd (0.27 ± 0.13), Mn (9.17 ± 1.50), and Co (1.09 ± 0.15). The level of Cr was below detection in all the samples analyzed. However, the levels of Ni, Mn, and Co investigated were all below the permissible limits set by FAO/WHO. The Cd concentrations of both cowpea types exceeded the FAO/WHO permissible limit of 0.2 mg/kg for cowpea. Determined heavy metal concentrations were used for potential health risk assessment in adults and children. The target hazard quotient and hazard index were >1 for Co, while the target cancer risk of Ni subsulfide for the cowpea types exceeded 10, and these results are causes for concern. It is recommended that the concentrations of the heavy metals in cowpea sold in Nigerian markets should be monitored regularly in order to avert their detrimental effects on consumers.
豇豆是一种植物蛋白来源,被尼日利亚民众广泛食用。本研究旨在评估尼日利亚 Gwagwalada 市场上销售的两种豇豆中重金属的健康风险。评估了两种豇豆类型的五种重金属镍(Ni)、镉(Cd)、锰(Mn)、钴(Co)和铬(Cr)的浓度。随机购买每种类型的样品,并使用原子吸收分光光度计分析重金属浓度(mg/kg)。褐色类型的重金属浓度(mg/kg 干重)如下:Ni(2.45±0.87)、Cd(0.26±0.10)、Mn(9.11±1.80)和 Co(1.67±0.20),而白色类型的浓度为:Ni(4.55±1.21)、Cd(0.27±0.13)、Mn(9.17±1.50)和 Co(1.09±0.15)。Cr 水平在所有分析的样品中均低于检测限。然而,所研究的 Ni、Mn 和 Co 水平均低于 FAO/WHO 设定的允许限值。两种豇豆类型的 Cd 浓度均超过 FAO/WHO 规定的 0.2mg/kg 豇豆允许限量。所确定的重金属浓度用于对成人和儿童进行潜在健康风险评估。Co 的目标危害商数和危害指数均>1,而 Ni 亚硫化物对豇豆类型的目标癌症风险超过 10,这些结果令人担忧。建议应定期监测尼日利亚市场上销售的豇豆中的重金属浓度,以避免对消费者产生不利影响。