Institute for Healthcare Improvement, Harvard T.H. Chan School of Public Health.
Fundación Avedis Donabedian.
Int J Qual Health Care. 2019 Nov 30;31(9):704-711. doi: 10.1093/intqhc/mzz051.
The incidence of central line-associated bloodstream infections (CLABSI) in Latin America has been estimated at 4.9 episodes per 1000 central line (CL) days, compared to a pooled incidence of 0.9 in the United States. CLABSI usually result from not adhering to standardized health procedures and can be prevented using evidence-based practices.
The first phase of the 'Adiós Bacteriemias' Collaborative was implemented in 39 intensive care units (ICUs) from Latin America from September 2012 to September 2013 with a 56% overall reduction in the incidence of CLABSI.
Bundles of care for the processes of insertion and maintenance of CLs have proven to be effective in the reduction of CLABSI across different settings.
Building on the results of the first phase, we implemented a second phase of the 'Adiós Bacteriemias' Collaborative between June 2014-July 2015. We adapted the Breakthrough Series (BTS) Collaborative model to guide the adoption of bundles of care for CLABSI prevention through virtual learning sessions and continuous feedback.
Eighty-three ICUs from five Latin American countries actively reported process and outcome measures. The overall reduction in the CLABSI incidence rate was 22% (incidence rate 0.78; 95% CI 0.65, 0.95), from 2.58 episodes per 1000 CL days at baseline to 2.02 episodes per 1000 CL days (P < 0.01) during the intervention period.
Adiós Bacteriemias was effective in reducing the incidence of CLABSI and improving the adherence to good practices for CL insertion and maintenance processes in participating ICUs in Latin America.
据估计,拉丁美洲中心静脉导管相关血流感染(CLABSI)的发生率为每 1000 个中心静脉导管(CL)日 4.9 例,而美国的汇总发生率为 0.9。CLABSI 通常是由于不遵守标准化卫生程序引起的,可以通过使用循证实践来预防。
“Adiós Bacteriemias”合作的第一阶段于 2012 年 9 月至 2013 年 9 月在拉丁美洲的 39 个重症监护病房(ICU)实施,总体 CLABSI 发生率降低了 56%。
CL 插入和维护过程的护理包已被证明在不同环境下有效降低 CLABSI 的发生率。
基于第一阶段的结果,我们在 2014 年 6 月至 2015 年 7 月之间实施了“Adiós Bacteriemias”合作的第二阶段。我们采用了突破性系列(BTS)合作模式来指导通过虚拟学习会议和持续反馈采用 CLABSI 预防护理包。
来自五个拉丁美洲国家的 83 个 ICU 积极报告了过程和结果指标。CLABSI 发生率的总体降低了 22%(发生率为 0.78;95%CI 0.65,0.95),从基线时的每 1000 个 CL 日 2.58 例降至干预期间的每 1000 个 CL 日 2.02 例(P < 0.01)。
“Adiós Bacteriemias”在降低 CLABSI 的发生率和改善参与拉丁美洲 ICU 的 CL 插入和维护过程的良好实践的依从性方面是有效的。