Department of Internal Medicine, Itoigawa General Hospital, Niigata, Japan.
Department of Surgery, Itoigawa General Hospital, Niigata, Japan.
Geriatr Gerontol Int. 2019 Aug;19(8):780-785. doi: 10.1111/ggi.13712. Epub 2019 Jun 14.
The present study was carried out to determine the reference ranges of 43 frequently used blood tests in daily practice for physically independent patients of advanced age.
We identified all patients aged ≥20 years who underwent groin hernia repair at Itoigawa General Hospital in Niigata, Japan. The patients' characteristics, preoperative data and prescribed medications were obtained by reviewing the electronic medical records.
Of 284 patients, 266 with independence in activities of daily life were included in the present study: 72 were assigned to the younger adult group (age 20-64 years), 86 were assigned to the older adult group (age 65-74 years) and 108 were assigned to the advanced age group (age ≥75 years). Patients in the advanced age group had a lower body mass index, less alcohol consumption, more hypertension, lower respiratory function and higher frequency of multidrug therapy. The multiple regression analysis showed significant differences in albumin, gamma-glutamyl transpeptidase, cholinesterase, estimated glomerular filtration rate, uric acid, triglyceride, calcium, phosphate, magnesium and peripheral blood cell counts between the advanced age group and the other two age groups.
We identified age-dependent changes in several blood tests among physically independent adults. These results will help to guide accurate interpretation of laboratory results and properly manage patients in geriatric medicine. Geriatr Gerontol Int 2019; 19: 780-785.
本研究旨在确定日常实践中 43 项常用血液检测在身体独立的高龄患者中的参考范围。
我们确定了在日本新潟县糸鱼川综合医院接受腹股沟疝修补术的所有年龄≥20 岁的患者。通过查看电子病历获得患者的特征、术前数据和规定的药物。
在 284 名患者中，有 266 名日常生活活动独立的患者被纳入本研究：72 名被分配到年轻成人组（年龄 20-64 岁），86 名被分配到老年成人组（年龄 65-74 岁），108 名被分配到高龄组（年龄≥75 岁）。高龄组患者的体重指数较低，饮酒较少，高血压、下呼吸道功能和多药物治疗的频率较高。多元回归分析显示，白蛋白、γ-谷氨酰转肽酶、胆碱酯酶、估算肾小球滤过率、尿酸、甘油三酯、钙、磷、镁和外周血细胞计数在高龄组与其他两组之间存在显著差异。
我们确定了身体独立的成年人中几项血液检测与年龄相关的变化。这些结果将有助于指导实验室结果的准确解释，并适当管理老年医学中的患者。老年医学杂志 2019; 19: 780-785。
