O'Dwyer Sabrina, Clark Anna, Taggart Hayley, Noori Muna
Maternity Department, Imperial College Healthcare NHS Trust, London, UK.
BMJ Open Qual. 2019 Apr 8;8(2):e000389. doi: 10.1136/bmjoq-2018-000389. eCollection 2019.
Induction of labour (IOL) is a common obstetric intervention. 32% of women are induced per year in our obstetric unit. We were experiencing delays in starting IOLs due to unit activity, protracted inpatient stay and dissatisfaction among staff and service users. We used quality improvement (QI) methodology to identify inefficiencies and root causes and used a bottom-up approach in planning improvements. After optimising our IOL processes, we introduced misoprostol vaginal insert (MVI) as it was faster acting than traditional dinoprostone. We compared 207 women who had MVI with 172 women who had dinoprostone prior to MVI introduction. There was a reduction of IOL start to delivery time, from a mean of 30 hours to 21 hours. Fewer women required oxytocin and of those who did, required oxytocin for fewer hours. We also found a reduction in caesarean section rates in women undergoing IOL, statistically significant in nulliparous women (41%-25%, p=0.03). There was a higher uterine tachysystole and hyperstimulation rate with MVI use and introduction should be accompanied by education of staff. We did not find any increase in neonatal admissions, maternal haemorrhage or other serious adverse events. In summary, MVI is a useful drug in helping high volume units with high IOL rates, reduced bed occupancy and improved flow of women. We would recommend a holistic QI approach to change management, as safe use of the drug requires optimisation of the IOL processes as well as staff engagement, due to rapid flow of women through the IOL pathway and increased hyperstimulation rates.
引产是一种常见的产科干预措施。在我们的产科病房,每年有32%的女性接受引产。由于科室工作繁忙、住院时间延长以及医护人员和服务使用者的不满,我们在开始引产方面遇到了延误。我们采用质量改进(QI)方法来识别效率低下问题和根本原因,并在规划改进措施时采用自下而上的方法。在优化引产流程后,我们引入了米索前列醇阴道栓剂(MVI),因为它的起效速度比传统的地诺前列酮更快。我们将207名使用MVI的女性与172名在引入MVI之前使用地诺前列酮的女性进行了比较。引产开始至分娩的时间有所缩短,从平均30小时降至21小时。需要催产素的女性减少了,而且那些需要催产素的女性,所需时间也减少了。我们还发现接受引产的女性剖宫产率有所降低,在未生育女性中具有统计学意义(从41%降至25%,p = 0.03)。使用MVI时子宫收缩过速和过度刺激的发生率较高,引入该药物时应伴有对医护人员的培训。我们未发现新生儿入院、产妇出血或其他严重不良事件有任何增加。总之,MVI对于帮助高引产率的大型科室减少床位占用和改善女性患者流程是一种有用的药物。我们建议采用整体的QI方法进行变革管理,因为由于女性在引产流程中流动迅速且过度刺激率增加,安全使用该药物需要优化引产流程以及医护人员的参与。