Nowak J S, Bacon L D, Rose N R
Arch Immunol Ther Exp (Warsz). 1978;26(1-6):279-82.
On the basis of performed studies the following observations indicate that there is a bursa-independent origin of lymphocytes with Fc IgG receptors: (a) the first appearance of Fc positive cells is in fetal liver and bone marrow, (b) a relative low percentage of Fc receptor cells, as compared to B cells, occurs in the bursa during the embryonic and post-hatching period, (c) a far lower percentage of Fc positive cells than B cells is found in the spleen, (d) a normal level of Fc positive cells occurs in bursectomized birds, (e) a majority of these cells do not possess thymic or bursa antigen or surface immunoglobulin.
基于已开展的研究,以下观察结果表明具有Fc IgG受体的淋巴细胞存在法氏囊非依赖起源:(a) Fc阳性细胞首次出现在胎儿肝脏和骨髓中;(b) 在胚胎期和孵化后期,与B细胞相比,法氏囊中Fc受体细胞的比例相对较低;(c) 在脾脏中发现的Fc阳性细胞比例远低于B细胞;(d) 在切除法氏囊的鸟类中,Fc阳性细胞水平正常;(e) 这些细胞中的大多数不具有胸腺或法氏囊抗原或表面免疫球蛋白。