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鞘内注射巴氯芬治疗痉挛:我院治疗病例回顾

Intrathecal baclofen as a treatment for spasticity: Review of the cases treated in our hospital.

作者信息

Santin-Amo José María, Flores-Justa Ana, Román-Pena Paula, Raposo-Furelos Martín, Frieiro-Dantas Carla, Serramito García Ramón, Villa Juan Manuel, Gelabert-González Miguel

机构信息

Servicio de Neurocirugía, Hospital Clínico Universitario de Santiago de Compostela, Departamento de Cirugía, Universidad de Santiago de Compostela, Santiago de Compostela, España.

Servicio de Neurocirugía, Hospital Clínico Universitario de Santiago de Compostela, Departamento de Cirugía, Universidad de Santiago de Compostela, Santiago de Compostela, España.

出版信息

Neurocirugia (Engl Ed). 2019 Nov-Dec;30(6):288-293. doi: 10.1016/j.neucir.2019.05.001. Epub 2019 Jun 14.

Abstract

INTRODUCTION

Spasticity represents a medical problem whose incidence is increasing during the last years due to pathologies such as cerebral palsy, stroke, multiple sclerosis, trauma or encephalopathy, affecting both adults and children. The treatments include rehabilitation, pharmacotherapy and surgery, among which we highlight intrathecal baclofen infusion devices.

MATERIAL AND METHODS

Intrathecal baclofen devices implanted patients in Clinical Hospital of Santiago de Compostela from 2005 to 2018 were selected for retrospective analysis using assessment of spasticity scales, such as Ashworth scale. Complications are described.

RESULTS

Surgery was performed in 17 patients for baclofen pump implant, achieving an improvement of 2 points on the Ashworth Scale in 88,2% of the patients and of 1 point on the Penn Scale in 94%. Complications were seen in 3 patients.

CONCLUSIONS

Intrathecal baclofen is a simple technique with good results for improving the quality of life of patients with spasticity.

摘要

引言

痉挛是一个医学问题,近年来由于诸如脑瘫、中风、多发性硬化症、创伤或脑病等病症,其发病率不断上升,影响着成人和儿童。治疗方法包括康复治疗、药物治疗和手术治疗,其中我们重点介绍鞘内注射巴氯芬输注装置。

材料与方法

选取2005年至2018年在圣地亚哥德孔波斯特拉临床医院植入鞘内巴氯芬装置的患者进行回顾性分析,采用痉挛量表评估,如Ashworth量表。描述了并发症情况。

结果

17例患者接受了巴氯芬泵植入手术,88.2%的患者Ashworth量表评分提高了2分,94%的患者Penn量表评分提高了1分。3例患者出现了并发症。

结论

鞘内注射巴氯芬是一种简单的技术,对于改善痉挛患者的生活质量有良好效果。

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