Toepffer Anne-Marie, Wecke Thoralf, Hoffmann Michael B, Thieme Hagen
Universitätsaugenklinik, Otto-von-Guericke-Universität, Magdeburg, Deutschland.
Universitätsaugenklinik, Universitätsklinikum Magdeburg A.ö.R., Leipziger Str. 44, 39120, Magdeburg, Deutschland.
Ophthalmologe. 2020 Apr;117(4):376-378. doi: 10.1007/s00347-019-0927-x.
The diagnostic findings, therapy and course of disease are described for a case of central venous occlusion in Wyburn-Mason-Syndrome. The diagnosis was based on OCT, fluorescein angiography and cMRI. In addition, due to the macular edema an intravitreal injection with Ranibizumab was applied. The macular edema regressed and further Ranibizumab-injections as well as a panretinal laser-coagulation and possibly a cryocoagulation were planned. For a central venous occlusion with macular edema also in Wyburn-Mason-Syndrome an intravitreal anti-VEGF-inhibition leads to an improvement.
本文描述了一例怀伯恩-梅森综合征(Wyburn-Mason-Syndrome)合并中心静脉阻塞患者的诊断结果、治疗方法及病程。诊断基于光学相干断层扫描(OCT)、荧光素血管造影和磁共振成像(cMRI)。此外,由于存在黄斑水肿,给予了玻璃体内注射雷珠单抗治疗。黄斑水肿消退,计划进一步注射雷珠单抗以及进行全视网膜激光光凝,可能还需进行冷冻治疗。对于怀伯恩-梅森综合征合并黄斑水肿的中心静脉阻塞,玻璃体内抗血管内皮生长因子(VEGF)抑制治疗可使病情改善。