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后部可逆性脑病综合征的脑电图表现。

EEG Findings in Posterior Reversible Encephalopathy Syndrome.

机构信息

1 University of South Florida, Tampa, FL, USA.

出版信息

Clin EEG Neurosci. 2019 Sep;50(5):366-369. doi: 10.1177/1550059419856968. Epub 2019 Jun 19.

Abstract

. Posterior reversible encephalopathy syndrome (PRES) is a relatively common cause of encephalopathy in the hospital setting, and the EEG findings have not been well described. The purpose of this study was to review the EEG findings in a series of patients with PRES. . We retrospectively reviewed our electronic medical record database to identify patients who received a diagnosis of PRES at Tampa General Hospital from January 2016 to October 2017. The diagnosis of PRES was suspected on clinical presentation and confirmed by magnetic resonance imaging. We selected patients with PRES who had received at least 1 EEG. EEGs were interpreted by 2 board-certified electroencephalographers. . From January 2016 to October 2017, 19 patients were diagnosed with PRES at Tampa General Hospital. Of those, 10 received at least 1 EEG. Four patients were male, 6 were female. The ages ranged from 21 to 87 (mean was 47). The patients had the following clinical presentations: 5 with encephalopathy, 8 with seizures, 2 with vision changes, and 3 with headache (some patients had more than 1 symptom). EEGs findings were as follows: 3 were normal; 3 showed intermittent generalized slowing; 2 showed continuous generalized slowing; 3 showed background slowing; 1 showed background suppression; 1 showed generalized rhythmic delta activity (GRDA); 1 showed GRDA, plus spike/sharp-wave discharges; 1 showed generalized periodic discharges. The etiologies were as follows: 9 from hypertension, 1 secondary to eclampsia, 3 due to posttransplant immunosuppression, and 1 patient was undergoing chemotherapy (some were multifactorial). . EEG findings in PRES are diverse, with no specific or even predominant pattern, based on this small sample size.

摘要

后部可逆性脑病综合征(PRES)是医院环境中一种相对常见的脑病病因,其脑电图表现尚未得到很好的描述。本研究旨在回顾一系列 PRES 患者的脑电图表现。

我们通过回顾性分析电子病历数据库,确定了 2016 年 1 月至 2017 年 10 月期间坦帕总医院(Tampa General Hospital)诊断为 PRES 的患者。PRES 的诊断依据临床表现,并通过磁共振成像(MRI)确认。我们选择了至少接受过 1 次脑电图(EEG)检查的 PRES 患者。脑电图由 2 名具有脑电图检查资质的脑电图技师进行解读。

2016 年 1 月至 2017 年 10 月期间,坦帕总医院共诊断了 19 例 PRES 患者,其中 10 例患者至少接受了 1 次脑电图检查。4 例男性,6 例女性;年龄范围为 21 岁至 87 岁(平均年龄为 47 岁)。患者的临床表现如下:5 例出现脑病,8 例出现癫痫发作,2 例出现视力改变,3 例出现头痛(部分患者出现多种症状)。脑电图结果如下:3 例正常,3 例表现为间歇性广泛慢波,2 例表现为连续广泛慢波,3 例表现为背景慢波,1 例表现为背景抑制,1 例表现为广泛节律性 delta 活动(GRDA),1 例表现为 GRDA 合并棘波/尖波放电,1 例表现为广泛周期性放电。病因如下:9 例由高血压引起,1 例由子痫引起,3 例由移植后免疫抑制引起,1 例正在接受化疗(部分患者的病因是多因素的)。

基于本小样本量,PRES 的脑电图表现多样,无特定或甚至主要模式。

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