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接受带蒂面动脉岛状瓣重建术的腭部癌症年轻和老年患者的结局。

Outcomes of younger and older patients with palatal cancer undergoing pedicled facial-submental artery island flap reconstruction.

机构信息

Department of Oral and Maxillofacial Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.

Department of Oral and Maxillofacial Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.

出版信息

Int J Oral Maxillofac Surg. 2020 Jan;49(1):7-12. doi: 10.1016/j.ijom.2019.05.002. Epub 2019 Jun 18.

Abstract

The purpose of this study was to evaluate the outcomes of younger and older patients with palatal cancer undergoing reconstruction using the pedicled facial-submental artery island flap (FSAIF) following cancer ablation. Fifty-eight patients with palatal squamous cell carcinoma (SCC) were divided into two age groups: ≤60 years (n=31) and >60 years (n=27). By clinical SCC stage, 6.4%, 83.9%, and 9.7% of the younger group and 3.7%, 85.2%, and 11.1% of the older group were stage I, II, and III, respectively. The incidence of comorbid conditions was 35.5% (11/31) in those ≤60 years and 137.0% (37/27) in those >60 years. Brown class II maxillary defects (four class IIa, 44 class IIb, three class IIc, and seven class IId) were repaired using FSAIFs following cancer ablation. There were two flap failures; thus the success rate was 96.6%. Significant differences in mean age and the incidence of comorbid conditions were evident between the groups. No significant differences in TNM stage, maxillary defect classification, flap size, overall flap survival, rates of local and general complications, or survival status was evident between the groups. The FSAIF is a reliable and safe method for repairing Brown class II maxillary defects following cancer ablation, particularly in older patients.

摘要

本研究旨在评估接受癌症消融治疗后使用带蒂面动脉颏下岛状皮瓣(FSAIF)修复的年轻和老年硬腭癌患者的治疗结果。58 例硬腭鳞状细胞癌(SCC)患者分为两个年龄组:≤60 岁(n=31)和>60 岁(n=27)。根据临床 SCC 分期,年轻组的 6.4%、83.9%和 9.7%分别为 I 期、II 期和 III 期,而老年组分别为 3.7%、85.2%和 11.1%。≤60 岁患者中有 35.5%(11/31)存在合并症,而>60 岁患者中有 137.0%(37/27)存在合并症。FSAIF 用于修复癌症消融后的 Brown Ⅱ类上颌骨缺损(4 类 IIa、44 类 IIb、3 类 IIc 和 7 类 IId)。有两例皮瓣失败;因此,成功率为 96.6%。两组间平均年龄和合并症发生率存在显著差异。两组间 TNM 分期、上颌骨缺损分类、皮瓣大小、整体皮瓣存活率、局部和全身并发症发生率以及生存状况均无显著差异。FSAIF 是修复癌症消融后 Brown Ⅱ类上颌骨缺损的可靠且安全的方法,尤其适用于老年患者。

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