[局部晚期 Darier 病和费兰德皮肤纤维肉瘤的治疗结果：附 1 例病例及文献复习]
[Outcome of locally advanced Darier and Ferrand dermatofibrosarcoma: about a case and literature review].
作者信息
Ouahbi Hajar, Amadour Lamiae, Elmernissi Fatimazahra, Tahiri Layla, Harmouch Taoufik, Benbrahim Zineb, Elmrabet Fatimazahra, Arifi Samia, Oufkigh Ayat Allah, Mellas Nawfal
机构信息
Service d'Oncologie Médicale CHU Hassan II, Université Sidi Mohammed Ben Abdellah, Fès, Maroc.
Service de Dermatologie CHU Hassan II, Université Sidi Mohammed Ben Abdellah, Fès, Maroc.
出版信息
Pan Afr Med J. 2019 Feb 28;32:97. doi: 10.11604/pamj.2019.32.97.10293. eCollection 2019.
Darier and Ferrand dermatofibrosarcoma (DFS) is a rare skin tumor characterized by its local aggressiveness and a high risk of recurrences. Prognosis depends essentially on the quality of treatment. Complete response in Darier and Ferrand dermatofibrosarcoma with healthy margins, initially judged inoperable after 1 year of neoadjuvant imatinib-based treatment, has been rarely described in literature. We here report the case of a young female patient treated in the Department of Medical Oncology in FES for locally advanced DFS with complete response, in order to assess the role of imatinib and of targeted therapies in the treatment of DFS.
达里埃和费朗皮肤纤维肉瘤（DFS）是一种罕见的皮肤肿瘤，其特点是具有局部侵袭性和高复发风险。预后主要取决于治疗质量。在以伊马替尼为基础的新辅助治疗1年后最初判定无法手术切除的达里埃和费朗皮肤纤维肉瘤中，实现切缘阴性的完全缓解，这在文献中鲜有报道。我们在此报告一例年轻女性患者，其在FES医学肿瘤学部门接受治疗，患有局部晚期DFS并实现了完全缓解，目的是评估伊马替尼和靶向治疗在DFS治疗中的作用。
Zotero 插件