Department of Urology, New York University, New York, NY.
Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA.
Urology. 2019 Oct;132:202-206. doi: 10.1016/j.urology.2019.04.051. Epub 2019 Jun 20.
OBJECTIVE: To evaluate the presenting complications of patients to reconstructive urologists after masculinizing gender affirming genital reconstructive surgery (GRS) performed elsewhere. METHODS: We identified patients who underwent revision surgery by one of the co-authors for sequelae of masculinizing GRS. We reviewed patient demographics, medical history, details of prior GRS, and complications from GRS. Specific attention was paid to the presence of the following: suprapubic tube dependence, vaginal remnant, urethrocutaneous fistula (UCF) within the fixed urethra (pars fixa), UCF in the phallic urethra, phallic urethral stricture, meatal stenosis, and anastomotic urethral stricture. Statistical analysis was performed using the Fisher's exact test to determine differences in presenting symptoms by GRS. RESULTS: Fifty-five patients who had reconstructive surgery for complications from masculinizing GRS from September 2004 to September 2017 were identified. The median age at surgical correction was 33 years. Fifteen (27%) patients had prior metoidioplasty and 40 (73%) had prior phalloplasty. The median time from date of GRS to presentation to a reconstructive urologist was 4 months. Urethral strictures (n = 47, 86%) were the most common indication for subsequent surgery, followed by urethrocutaneous fistulae (n = 31, 56%) and vaginal remnant (n = 26, 47%). The majority of patients presented with 2 or more simultaneous complications (n = 40, 73%). CONCLUSION: There are several common presenting urologic complications after masculinizing GRS. Patients may present to reconstructive urologists early after GRS performed elsewhere. The long-term outcomes of GRS deserve further study.
目的:评估在其他地方进行男性化性别肯定生殖器重建手术后,患者向重建泌尿科医生就诊的表现并发症。
方法:我们确定了由其中一位合著者进行修正手术的患者,以治疗男性化 GRS 的后遗症。我们回顾了患者的人口统计学、病史、先前 GRS 的详细信息以及 GRS 的并发症。特别注意以下方面的情况:耻骨上导尿管依赖、阴道残端、固定尿道内的尿道皮瘘(固定段)、阴茎尿道内的尿道皮瘘、阴茎尿道狭窄、尿道口狭窄和吻合口尿道狭窄。使用 Fisher 精确检验进行统计分析,以确定 GRS 表现症状的差异。
结果:2004 年 9 月至 2017 年 9 月,我们确定了 55 名因男性化 GRS 并发症而接受重建手术的患者。手术矫正的中位年龄为 33 岁。15 名(27%)患者有先前的会阴成形术,40 名(73%)有先前的阴茎成形术。从 GRS 日期到向重建泌尿科医生就诊的中位时间为 4 个月。尿道狭窄(n=47,86%)是随后手术的最常见指征,其次是尿道皮瘘(n=31,56%)和阴道残端(n=26,47%)。大多数患者同时出现 2 种或多种并发症(n=40,73%)。
结论:男性化 GRS 后有几种常见的泌尿科表现并发症。患者可能在其他地方进行 GRS 后早期向重建泌尿科医生就诊。GRS 的长期结果值得进一步研究。
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