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肾动脉狭窄与充血性心力衰竭:我们究竟了解多少?

Renal Artery Stenosis and Congestive Heart Failure: What Do We Really Know?

机构信息

Division of Cardiovascular Medicine, College of Medicine and Life Sciences, University of Toledo, 3000 Arlington Ave, MS# 1118, Toledo, OH, 43614, USA.

Department of Medicine, College of Medicine and Life Sciences, University of Toledo, Toledo, OH, 43614, USA.

出版信息

Curr Cardiol Rep. 2019 Jun 24;21(8):74. doi: 10.1007/s11886-019-1169-x.

DOI:10.1007/s11886-019-1169-x
PMID:31236719
Abstract

PURPOSE OF REVIEW

Congestive heart failure (CHF) is a major cause of morbidity, mortality, and health care expenditure. Although the role of renal artery stenosis (RAS) in CHF has been known, there are a number of areas of uncertainty.

RECENT FINDINGS

The prevalence of RAS in subjects with CHF varies from 15 to 54% depending on the cohort studied and the diagnostic modality used to identify RAS. In subjects with CHF, the presence of RAS is associated with worse renal function and a higher risk for mortality during long-term follow-up. There are many unanswered questions regarding the role of RAS in subjects with CHF. This review highlights those questions and helps to set the research agenda in this area.

摘要

目的综述

充血性心力衰竭(CHF)是发病率、死亡率和医疗支出的主要原因。尽管肾动脉狭窄(RAS)在 CHF 中的作用已为人所知,但仍有许多不确定的领域。

最近的发现

根据研究队列和用于确定 RAS 的诊断方式,CHF 患者的 RAS 患病率从 15%到 54%不等。在 CHF 患者中,RAS 的存在与肾功能恶化和长期随访期间死亡率升高相关。关于 RAS 在 CHF 患者中的作用仍有许多尚未解答的问题。本综述强调了这些问题,并有助于确定该领域的研究议程。

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本文引用的文献

1
Renal Artery Stenosis: New Findings from the CORAL Trial.肾动脉狭窄:CORAL试验的新发现。
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Heart Disease and Stroke Statistics-2017 Update: A Report From the American Heart Association.《2017年心脏病和中风统计数据更新:美国心脏协会报告》
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Hemodynamic and neurochemical determinates of renal function in chronic heart failure.慢性心力衰竭时肾功能的血流动力学和神经化学决定因素
超声造影在慢性肾脏病患者肾动脉狭窄诊断及随访中的价值
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Renal artery stenosis: prevalence of, risk factors for, and management of in-stent stenosis.肾动脉狭窄:支架内狭窄的患病率、危险因素和处理。
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8
Atherosclerotic renal artery stenosis is prevalent in cardiorenal patients but not associated with left ventricular function and myocardial fibrosis as assessed by cardiac magnetic resonance imaging.动脉粥样硬化性肾动脉狭窄在心脏肾脏患者中较为普遍,但通过心脏磁共振成像评估,与左心室功能和心肌纤维化无关。
BMC Cardiovasc Disord. 2012 Sep 18;12:76. doi: 10.1186/1471-2261-12-76.
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