Division of Cardiovascular Medicine, College of Medicine and Life Sciences, University of Toledo, 3000 Arlington Ave, MS# 1118, Toledo, OH, 43614, USA.
Department of Medicine, College of Medicine and Life Sciences, University of Toledo, Toledo, OH, 43614, USA.
Curr Cardiol Rep. 2019 Jun 24;21(8):74. doi: 10.1007/s11886-019-1169-x.
Congestive heart failure (CHF) is a major cause of morbidity, mortality, and health care expenditure. Although the role of renal artery stenosis (RAS) in CHF has been known, there are a number of areas of uncertainty.
The prevalence of RAS in subjects with CHF varies from 15 to 54% depending on the cohort studied and the diagnostic modality used to identify RAS. In subjects with CHF, the presence of RAS is associated with worse renal function and a higher risk for mortality during long-term follow-up. There are many unanswered questions regarding the role of RAS in subjects with CHF. This review highlights those questions and helps to set the research agenda in this area.
充血性心力衰竭(CHF)是发病率、死亡率和医疗支出的主要原因。尽管肾动脉狭窄(RAS)在 CHF 中的作用已为人所知,但仍有许多不确定的领域。
根据研究队列和用于确定 RAS 的诊断方式,CHF 患者的 RAS 患病率从 15%到 54%不等。在 CHF 患者中,RAS 的存在与肾功能恶化和长期随访期间死亡率升高相关。关于 RAS 在 CHF 患者中的作用仍有许多尚未解答的问题。本综述强调了这些问题,并有助于确定该领域的研究议程。