Department of Pulmonary Disease, Faculty of Medicine, Ataturk University, Yakutiye, 25240, Erzurum, Turkey.
Department of Radiology, Faculty of Medicine, Ataturk University, Erzurum, Turkey.
Sleep Breath. 2020 Jun;24(2):465-470. doi: 10.1007/s11325-019-01879-3. Epub 2019 Jun 26.
Obstructive sleep apnea syndrome (OSAS) is a condition resulting from repetitive partial or complete upper airway obstruction, and its etiology remains uncertain. Polysomnography is the gold standard diagnostic test for OSAS. However, there are long wait times for this evaluation, so questionnaires or ancillary diagnostic methods are used to select appropriate patients. One of these is magnetic resonance imaging (MRI). The present study aimed to investigate the association between clinical features of OSAS and uvular changes on MRI.
A total of 102 participants, 80 with OSAS and 22 controls, were included in the study. All participants underwent full-night polysomnography, MRI, and anthropometric measurements.
In comparisons of MRI measurements of the uvula, statistically significant differences in uvular length, thickness, and angle were observed between the OSAS and control groups. MRI measurement significantly associated with apnea-hypopnea index was uvular thickness. Evaluation of anthropometric and MRI measurements revealed statistically significant associations between waist circumference and uvular thickness, uvular width, and oropharyngeal space among the OSAS patients.
Thickened uvula on MRI is associated with the presence of OSAS, and its thickness is well correlated with the severity of the diseases. Thus, it may be a reliable indicator of OSAS and could be used as a supportive finding to identify patients suitable for referral for diagnostic polysomnography.
阻塞性睡眠呼吸暂停综合征(OSAS)是一种由上呼吸道反复部分或完全阻塞引起的疾病,其病因仍不确定。多导睡眠图是 OSAS 的金标准诊断测试。然而,这种评估的等待时间很长,因此使用问卷或辅助诊断方法来选择合适的患者。其中之一是磁共振成像(MRI)。本研究旨在探讨 OSAS 的临床特征与 MRI 上悬雍垂变化之间的关系。
共有 102 名参与者(80 名 OSAS 患者和 22 名对照组)纳入本研究。所有参与者均接受了整夜多导睡眠图、MRI 和人体测量。
在 MRI 测量悬雍垂的比较中,OSAS 组和对照组之间观察到悬雍垂长度、厚度和角度存在统计学显著差异。与呼吸暂停低通气指数显著相关的 MRI 测量是悬雍垂厚度。对人体测量和 MRI 测量的评估表明,在 OSAS 患者中,腰围与悬雍垂厚度、悬雍垂宽度和口咽腔空间之间存在统计学显著关联。
MRI 上的增厚悬雍垂与 OSAS 的存在相关,其厚度与疾病的严重程度密切相关。因此,它可能是 OSAS 的可靠指标,并可作为识别适合进行诊断性多导睡眠图检查的患者的辅助发现。