Department of Pathology, Johns Hopkins Hospital and Health System, Baltimore, MD.
Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN.
Am J Clin Pathol. 2019 Sep 9;152(4):537-541. doi: 10.1093/ajcp/aqz071.
Recently published data suggest that transfusion of RBCs stored for 22 days or longer was associated with increased mortality among massively transfused trauma patients.
We performed a 24-month retrospective review of medical transport service transfusion records and a 2-month, overlapping review of transfusions of uncrossmatched RBCs in the emergency department.
RBC units issued to the transport program were older than RBC units issued to the emergency department trauma refrigerator (10.6 vs 8.7 days, P < .001). Similarly, RBC units were older at the time of transfusion during transport compared with the emergency department (20.3 vs 14.3 days, P < .001).
Transport programs and blood banks should jointly review their RBC inventory management programs. Issuing RBCs to a medical transport program is a logistical challenge that, unless actively managed, may not ensure access to blood that is as fresh as blood in the emergency department.
最近公布的数据表明,输注储存 22 天或更长时间的红细胞与大量输血创伤患者的死亡率增加有关。
我们对医疗运输服务的输血记录进行了为期 24 个月的回顾性研究,并对急诊部未交叉配血的红细胞输血进行了为期 2 个月的重叠回顾性研究。
发放给运输项目的红细胞单位比发放给急诊部创伤冰箱的红细胞单位陈旧(10.6 天 vs. 8.7 天,P <.001)。同样,在运输过程中进行输血时的红细胞单位比在急诊部时更陈旧(20.3 天 vs. 14.3 天,P <.001)。
运输项目和血库应共同审查其红细胞库存管理计划。向医疗运输计划发放红细胞是一个后勤挑战,如果不积极管理,可能无法确保获得与急诊部一样新鲜的血液。