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生育酚、三烯生育酚和生育三烯酚:多种类似分子,唯有维生素 E 一种。

Tocopherols, tocotrienols and tocomonoenols: Many similar molecules but only one vitamin E.

机构信息

Sackler School of Graduate Biomedical Pharmacology and Drug Development Program, Tufts University, 75 Kneeland Street, Boston, MA, 02111, USA.

出版信息

Redox Biol. 2019 Sep;26:101259. doi: 10.1016/j.redox.2019.101259. Epub 2019 Jun 19.

Abstract

The aim of this article is to correct a very general error in scientific articles, in textbooks and in the Internet that has become an accepted fact. In this literature, the term "vitamin E″ is used for several similar molecules (both tocopherols and tocotrienols) that have never been shown to have vitamin property, i.e. a protective effect against the human deficiency disease. In fact, the name "vitamin E″ should only be used to define molecules that prevent the human deficiency disease "Ataxia with Vitamin E Deficiency" (AVED). Only one such molecule is known, α-tocopherol. This error may confuse consumers as well as medical doctors, who prescribe vitamin E without realizing that the current use of the name includes molecules of unknown, if not unwanted functions.

摘要

本文旨在纠正科学文献、教材和互联网上一个非常普遍的错误,该错误已成为公认的事实。在该文献中,术语“维生素 E”用于几种类似的分子(生育酚和三烯生育酚),这些分子从未被证明具有维生素特性,即对人类营养缺乏症的保护作用。事实上,“维生素 E”这个名称应该只用于定义能够预防人类营养缺乏症“维生素 E 缺乏性共济失调”(AVED)的分子。目前已知只有一种这样的分子,即α-生育酚。这个错误可能会使消费者和医生感到困惑,因为他们在开维生素 E 时没有意识到,目前对这个名称的使用包括了一些功能未知,甚至可能是不需要的分子。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4327/6604160/69181c0739a7/fx1.jpg

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