上颌骨在单侧唇腭裂术后青春期结束时的形态：基于计算机断层扫描的几何形态测量评估。
Maxillary shape at the end of puberty in operated unilateral cleft lip and palate: A geometric morphometric assessment using computer tomography.
机构信息
Service de Chirurgie Maxillofaciale et Chirurgie Plastique, filière maladies rares TeteCou, centre de référence maladies rares MAFACE, Hôpital Universitaire Necker-Enfants Malades, Université Sorbonne Paris-Cité, Université Paris-Descartes, AP-HP, 75015 Paris, France.
Service de Chirurgie Maxillofaciale et Chirurgie Plastique, filière maladies rares TeteCou, centre de référence maladies rares MAFACE, Hôpital Universitaire Necker-Enfants Malades, Université Sorbonne Paris-Cité, Université Paris-Descartes, AP-HP, 75015 Paris, France.
出版信息
J Stomatol Oral Maxillofac Surg. 2020 Feb;121(1):9-13. doi: 10.1016/j.jormas.2019.06.004. Epub 2019 Jun 27.
INTRODUCTION
Cleft lip and palate (CLP) surgery interferes with maxillary growth and contributes to transversal and sagittal growth impairment. Our retrospective descriptive study aimed to evaluate maxillary bone shape in a homogenous unilateral CLP patient group using geometric morphometrics based on CT-scan data.
MATERIAL AND METHODS
We included all patients with available CT-scans at the end of pubertal growth and operated on at Smile House of Milan, according to the standard protocol, involving two surgical steps: (1) primary closure of the lip and soft palate at 6 months of age and (2) early secondary gingivoalveoloplasty (GAP) associated with hard palate repair at 18-36 months. Shape differences between CLP and an age-matched control group were characterized using geometric morphometrics based on 15 3D landmarks.
RESULTS
We included 16 unilateral CLP patients and 20 age-matched controls. Principal component and canonical variate analyses showed that the maxillary shape in CLP was significantly different from controls but that this difference was limited. Linear and angular measurements confirmed these differences.
CONCLUSION
Early secondary GAP results in satisfactory maxillary shape, with significant but limited differences relative to controls.
简介
唇腭裂（CLP）手术会干扰上颌骨的生长，导致横向和矢状生长受损。我们的回顾性描述性研究旨在使用基于 CT 扫描数据的几何形态测量学来评估同一致单侧 CLP 患者群体的上颌骨形状。
材料和方法
我们纳入了所有在青春期生长结束时可获得 CT 扫描且根据 Smile House of Milan 的标准方案接受手术的患者，该方案包括两个手术步骤：（1）在 6 个月大时进行唇和软腭裂的初次闭合，（2）在 18-36 个月时进行早期二次牙龈牙槽成形术（GAP）并同时修复硬腭。使用基于 15 个 3D 标志点的几何形态测量学，对 CLP 和年龄匹配的对照组之间的形状差异进行了描述。
结果
我们纳入了 16 例单侧 CLP 患者和 20 名年龄匹配的对照组。主成分和典型变量分析表明，CLP 患者的上颌骨形状与对照组明显不同，但这种差异是有限的。线性和角度测量结果证实了这些差异。
结论
早期二次 GAP 可获得满意的上颌骨形状，与对照组相比存在显著但有限的差异。
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