实施一项临床指南以减少对疑似早发型败血症的新生儿进行的实验室检查。
Implementation of a clinical guideline to decrease laboratory tests in newborns evaluated for early onset sepsis.
作者信息
Le C N, Sauer C W, Law C, Proudfoot J A, Song R S
机构信息
Department of Pediatrics, University of California San Diego, Rady Children's Hospital of San Diego, Division of Perinatal-Neonatal Medicine, San Diego, CA, USA.
University of California San Diego, Department of Clinical and Translational Research Institute, San Diego, CA, USA.
出版信息
J Neonatal Perinatal Med. 2019;12(4):443-448. doi: 10.3233/NPM-180181.
BACKGROUND
Creation of a clinical guideline to reduce the number of complete blood counts (CBCs) obtained on healthy term infants for early onset sepsis (EOS) evaluation secondary to maternal chorioamnionitis.
METHODS
A clinical guideline was introduced at four neonatal intensive care units (NICU) to reduce laboratory tests during EOS evaluation. Measures include frequency and timing of CBCs, culture negative sepsis, length of stay, and readmission rate.
RESULTS
Mean number of CBCs per patient significantly decreased (2.31±0.62 versus 1.52±0.65) without increasing trends for patients with culture negative sepsis, length of stay, or re-admission.
CONCLUSION
The clinical guideline demonstrated a significant reduction in the number of CBCs obtained in well-appearing infants admitted to the NICU secondary to maternal chorioamnionitis.
背景
制定一项临床指南，以减少因母亲绒毛膜羊膜炎而对健康足月儿进行早发型败血症（EOS）评估时所进行的全血细胞计数（CBC）次数。
方法
在四个新生儿重症监护病房（NICU）引入一项临床指南，以减少EOS评估期间的实验室检查。措施包括CBC的频率和时间、培养阴性败血症、住院时间和再入院率。
结果
每位患者的平均CBC次数显著减少（2.31±0.62对1.52±0.65），而培养阴性败血症患者、住院时间或再入院率均无增加趋势。
结论
该临床指南表明，因母亲绒毛膜羊膜炎而入住NICU的外观良好婴儿所进行的CBC次数显著减少。
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