Walsh Thomas J, Hospenthal Duane R, Petraitis Vidmantas, Kontoyiannis Dimitrios P
Departments of Medicine, Pediatrics, and Microbiology & Immunology; Weill Cornell Medicine of Cornell University and New York Presbyterian Hospital, New York, NY 10065, USA.
Division of Infectious Diseases, Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
J Fungi (Basel). 2019 Jul 4;5(3):57. doi: 10.3390/jof5030057.
Necrotizing mucormycosis is a devastating complication of wounds incurred in the setting of military (combat) injuries, natural disasters, burns, or other civilian trauma. species, species and (formerly species, although uncommon as causes of sinopulmonary mucormycosis, are relatively frequent agents of trauma-related mucormycosis. The pathogenesis of these infections likely involves a complex interaction among organism, impaired innate host defenses, and biofilms related to traumatically implanted foreign materials. Effective management depends upon timely diagnosis, thorough surgical debridement, and early initiation of antifungal therapy.
坏死性毛霉病是军事(战斗)伤、自然灾害、烧伤或其他平民创伤所致伤口的一种毁灭性并发症。根霉菌属、毛霉菌属和犁头霉菌属(以前为根霉菌属,虽然作为鼻窦肺毛霉病的病因并不常见,但却是创伤相关毛霉病相对常见的病原体。这些感染的发病机制可能涉及病原体、宿主固有防御受损以及与创伤植入异物相关的生物膜之间的复杂相互作用。有效的治疗取决于及时诊断、彻底的手术清创以及早期开始抗真菌治疗。