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肌萎缩侧索硬化症患者脑脊液中的游离氨基酸模式

Free amino acid pattern of cerebrospinal fluid in amyotrophic lateral sclerosis.

作者信息

Meier D H, Schott K J

机构信息

Neurology Clinic, Tübingen University, West Germany.

出版信息

Acta Neurol Scand. 1988 Jan;77(1):50-3. doi: 10.1111/j.1600-0404.1988.tb06973.x.

Abstract

The concentrations of 23 amino acids (AA) were measured in CSF of patients with Amyotrophic Lateral Sclerosis (ALS). A micro-method with picomole sensitivity was used. Compared with healthy controls no significant alterations of single or total AA concentrations were found. These results contrast with data published in a previous study and will be discussed in detail.

摘要

对肌萎缩侧索硬化症(ALS)患者脑脊液中的23种氨基酸(AA)浓度进行了测量。采用了具有皮摩尔灵敏度的微量方法。与健康对照相比,未发现单个或总氨基酸浓度有显著变化。这些结果与先前一项研究中发表的数据形成对比,并将进行详细讨论。

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