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老年骨科中股骨上段骨折手术时机的影响。

Impact of time to surgery in upper femoral fracture in orthogeriatrics.

机构信息

Service de Chirurgie Orthopédique et Traumatologie, CHU de Poitiers, 2, rue de la Milétrie, Poitiers, 86000 France.

Service de Chirurgie Orthopédique et Traumatologie, CHU de Poitiers, 2, rue de la Milétrie, Poitiers, 86000 France.

出版信息

Orthop Traumatol Surg Res. 2019 Sep;105(5):975-978. doi: 10.1016/j.otsr.2019.04.018. Epub 2019 Jul 10.

Abstract

INTRODUCTION

Treatment of hip fracture in the elderly is a major public health issue. Orthogeriatric departments have been developed for these patients at high risk of complications. Time to surgery seems to be an important factor in the care pathway, but remains controversial.

OBJECTIVES

The aim of this study was to assess the impact of less than 24 hours' time to surgery on 1-year morbidity and mortality in patients managed in our orthogeriatric department.

HYPOTHESIS

The study hypothesis was that<24 hours' time to surgery decreases mortality in elderly patients with upper femoral fracture.

MATERIALS AND METHODS

A retrospective cohort study from September 2015 to July 2016 included patients aged 75 years and older, eligible for orthogeriatric management of upper femoral fracture. Patients with comorbidities were prioritized for admission and for access to the operating room. Time to surgery was defined as time between the arrival in A&E and transfer to the operating room. The primary endpoint was 1-year survival. Comorbidities were assessed on Charlson score. ROC curve analysis determined the optimal cut-off for time to surgery. Variables significantly associated with mortality were included in a Cox regression model to estimate the adjusted effect of time to surgery on mortality.

RESULTS

One hundred and eight patients were included; mean age, 87±6.2 years; 26 male (24.1%), 82 female (75.9%). One-year mortality was 24.1% (26/108). Mean time to surgery was 14.1±30.9hours. ROC curve analysis showed a rise in mortality after a cut-off of 22hours 37minutes (p<0.0001).

CONCLUSION

Within a dedicated orthogeriatric department, time to surgery is a significant factor in the management of hip fractures in the elderly. Patients should be prioritized for theater and ideally receive "early" surgery within 24hours of admission to A&E. The potential benefit of "ultra-early" surgery (time to surgery<6hours) requires robust assessment.

LEVEL OF EVIDENCE

IV, Retrospective cohort study.

摘要

引言

老年人髋部骨折的治疗是一个主要的公共卫生问题。为这些高并发症风险的患者设立了矫形老年病科。手术时间似乎是护理路径中的一个重要因素,但仍存在争议。

目的

本研究旨在评估我们矫形老年病科管理的患者中,手术时间少于 24 小时对 1 年发病率和死亡率的影响。

假设

研究假设是<24 小时的手术时间可降低老年股骨上段骨折患者的死亡率。

材料和方法

这是一项回顾性队列研究,纳入了 2015 年 9 月至 2016 年 7 月年龄在 75 岁及以上、符合矫形老年病科股骨上段骨折管理条件的患者。有合并症的患者优先入院和进入手术室。手术时间定义为从急诊到达至转入手术室的时间。主要终点是 1 年生存率。合并症用 Charlson 评分评估。ROC 曲线分析确定手术时间的最佳截断值。将与死亡率显著相关的变量纳入 Cox 回归模型,以估计手术时间对死亡率的调整影响。

结果

共纳入 108 例患者;平均年龄 87±6.2 岁;26 例男性(24.1%),82 例女性(75.9%)。1 年死亡率为 24.1%(26/108)。平均手术时间为 14.1±30.9 小时。ROC 曲线分析显示,在截断值为 22 小时 37 分钟后,死亡率上升(p<0.0001)。

结论

在专门的矫形老年病科中,手术时间是老年人髋部骨折管理的一个重要因素。应优先为患者安排手术室,并理想情况下在急诊就诊后 24 小时内进行“早期”手术。“超早期”手术(手术时间<6 小时)的潜在获益需要进行严格评估。

证据等级

IV,回顾性队列研究。

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