Immunisation, Hepatitis, Blood Safety and Countermeasures Response National Infection Service, Public Health England, London, UK.
Paediatrics, University of Oxford, Oxford, UK.
Arch Dis Child. 2020 Mar;105(3):216-222. doi: 10.1136/archdischild-2019-317707. Epub 2019 Jul 13.
The centrally coordinated response that controlled the polio epidemics of the 1950s through immunisation led to the development of a national immunisation strategy in the UK and the formation of the Joint Committee on Vaccination and Immunisation (JCVI) in 1963, which oversees the immunisation programme and advises the UK Department of Health on new vaccine introductions. As a result of technological advances in vaccine development and scientific advances in immunology and microbiology over the 56 years since then, and the formation of a comprehensive public health surveillance system for vaccine-preventable disease, the National Health Service immunisation programme now covers 18 serious diseases of childhood, with an astonishing impact on child health. Here we consider the formation of the JCVI and the development of the national immunisation programme and review the introduction of vaccines over the past half century to defend public health.
通过免疫接种来控制 20 世纪 50 年代脊髓灰质炎疫情的中央协调反应,促使英国制定了国家免疫接种战略,并于 1963 年成立了疫苗接种和免疫联合委员会(JCVI),该委员会负责监督免疫接种计划,并就新疫苗的引入向英国卫生部提供建议。自那以后,疫苗开发方面的技术进步、免疫学和微生物学方面的科学进步,以及疫苗可预防疾病的全面公共卫生监测系统的建立,使国民保健制度的免疫接种计划现在涵盖了 18 种严重的儿童疾病,对儿童健康产生了惊人的影响。在这里,我们考虑了 JCVI 的成立和国家免疫接种计划的发展,并回顾了过去半个世纪以来为维护公共卫生而引入的疫苗。