Walker Sarah, Bisseling Catharina, Curpad Sanjay, Edwards Gareth
Department of Obstetrics and Gynaecology, Royal Gwent Hospital, Aneurin Bevan University Health Board , Newport , UK.
J Obstet Gynaecol. 2019 Nov;39(8):1143-1147. doi: 10.1080/01443615.2019.1603206. Epub 2019 Jul 13.
A survey was circulated to consultant gynaecologists across Wales, to evaluate the management of pre-operative urine dipstick results. Questions were based on NICE guideline 171, regarding the management of urinary incontinence in women. Six respondents never checked their patient's urine dipstick results. Of the remaining 37 respondents, 70% always check and 30% sometimes check. Overall, 37.1% cancelled surgery when a urine dipstick was positive for either nitrite or leukocyte-esterase (LE). A significantly larger proportion cancelled surgery when symptomatic for urinary tract infection (< 0.001), and when nitrite and LE positive compared to only LE positive (< 0.05). This survey provides evidence that gynaecological operations are potentially being cancelled unnecessarily based on a screening test with limited sensitivity and specificity. Further research is needed into the outcomes of gynaecological surgery in women symptomatic of urinary tract infection to provide guidance on the use of pre-operative urinalysis and the management of test results. Impact statement The strongest risk factor for postoperative urinary tract infections (UTIs) is a pre-operative recurrent UTI (Nygaard et al. 2011 ). This is the reason behind the urine dipstick being part of the pre-operative checklist for gynaecological surgery. Traditionally, a suspected UTI would mean postphoning surgery whilst treating the UTI. It is known that the sensitivity of the nitrite test and leukocyte-esterase test when used alone is low and cannot rule out UTI in most patients (Mambatta et al. 2015 ). Urine culture is therefore suggested for all patients with a suspected UTI (John et al. 2006 ). To our knowledge, there are no data available on whether we should be postphoning gynaecological surgery based on a urine dipstick result. Overall, 37.1% of respondents cancelled surgery when a pre-operative urine dipstick was positive for either nitrite or leukocyte-esterase. This provides evidence of variation in the practice of using the urine dipstick in women undergoing gynaecological surgery in Wales. These cancellations are potentially unnecessarily. Furthermore, 14% of respondents did not use a urine dipstick and the majority did not act on an abnormal results, implying clinicians have a low confidence in the test as a screening tool. We propose removing the urine dipstick as a pre-operative screening test. Asymptomatic bacteriuria is common in women and routine screening for UTI pre-operatively will therefore inevitably lead to unnecessary intervention (i.e. cancellation). Further research is needed into the outcomes of gynaecological surgery in women symptomatic of UTI to be able to provide guidance on the use of pre-operative urinalysis and management of the test results.
一项调查问卷在威尔士的妇科顾问医生中进行了分发,以评估术前尿试纸检测结果的管理情况。问题基于英国国家卫生与临床优化研究所(NICE)关于女性尿失禁管理的第171号指南。6名受访者从不查看患者的尿试纸检测结果。在其余37名受访者中,70%总是查看,30%有时查看。总体而言,当尿试纸检测亚硝酸盐或白细胞酯酶(LE)呈阳性时,37.1%的受访者取消了手术。当患者有尿路感染症状时取消手术的比例显著更高(<0.001),并且当亚硝酸盐和LE均为阳性时相比仅LE阳性时取消手术的比例更高(<0.05)。这项调查提供了证据表明,基于一项敏感性和特异性有限的筛查测试,妇科手术可能被不必要地取消。需要对有尿路感染症状的女性进行妇科手术的结果进行进一步研究,以就术前尿液分析的使用和检测结果的管理提供指导。影响声明 术后尿路感染(UTI)的最强风险因素是术前复发性UTI(Nygaard等人,2011年)。这就是尿试纸成为妇科手术术前检查清单一部分的原因。传统上,疑似UTI意味着推迟手术同时治疗UTI。众所周知,单独使用亚硝酸盐测试和白细胞酯酶测试的敏感性较低,在大多数患者中无法排除UTI(Mambatta等人,2015年)。因此建议对所有疑似UTI的患者进行尿培养(John等人,2006年)。据我们所知,没有关于是否应基于尿试纸检测结果推迟妇科手术的数据。总体而言,当术前尿试纸检测亚硝酸盐或白细胞酯酶呈阳性时,37.1%的受访者取消了手术。这提供了证据表明在威尔士接受妇科手术的女性中使用尿试纸的做法存在差异。这些取消手术的情况可能是不必要的。此外,14%的受访者未使用尿试纸,并且大多数人对异常结果未采取行动,这意味着临床医生对该测试作为筛查工具的信心较低。我们建议取消将尿试纸作为术前筛查测试。无症状菌尿在女性中很常见,因此术前常规筛查UTI将不可避免地导致不必要的干预(即取消手术)。需要对有UTI症状的女性进行妇科手术的结果进行进一步研究,以便能够就术前尿液分析的使用和检测结果的管理提供指导。