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WT1 as an immunotherapy target for thymic epithelial tumors: a novel method to activate anti-tumor immunity.

作者信息

Takahashi Nobuyuki, Zhao Chen, Rajan Arun

机构信息

Thoracic and Gastrointestinal Malignancies Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.

出版信息

Mediastinum. 2019 Apr;3. doi: 10.21037/med.2019.03.03. Epub 2019 Apr 8.

Abstract
摘要

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本文引用的文献

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Phase I/II clinical trial of a Wilms' tumor 1-targeted dendritic cell vaccination-based immunotherapy in patients with advanced cancer.
Cancer Immunol Immunother. 2019 Jan;68(1):121-130. doi: 10.1007/s00262-018-2257-2. Epub 2018 Oct 10.
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Pembrolizumab for Patients With Refractory or Relapsed Thymic Epithelial Tumor: An Open-Label Phase II Trial.
J Clin Oncol. 2019 Aug 20;37(24):2162-2170. doi: 10.1200/JCO.2017.77.3184. Epub 2018 Jun 15.
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The Integrated Genomic Landscape of Thymic Epithelial Tumors.
Cancer Cell. 2018 Feb 12;33(2):244-258.e10. doi: 10.1016/j.ccell.2018.01.003.
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Pembrolizumab in patients with thymic carcinoma: a single-arm, single-centre, phase 2 study.
Lancet Oncol. 2018 Mar;19(3):347-355. doi: 10.1016/S1470-2045(18)30062-7. Epub 2018 Jan 26.
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WT1 peptide-based immunotherapy for advanced thymic epithelial malignancies.
Int J Cancer. 2018 Jun 1;142(11):2375-2382. doi: 10.1002/ijc.31253. Epub 2018 Jan 21.
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Transient Treg depletion enhances therapeutic anti-cancer vaccination.
Immun Inflamm Dis. 2016 Nov 21;5(1):16-28. doi: 10.1002/iid3.136. eCollection 2017 Mar.

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