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小儿心脏手术后延迟胸骨闭合患者手术部位感染的最小化

Minimization of Surgical Site Infections in Patients With Delayed Sternal Closure After Pediatric Cardiac Surgery.

作者信息

Yabrodi Mouhammad, Hermann Jeremy L, Brown John W, Rodefeld Mark D, Turrentine Mark W, Mastropietro Christopher W

机构信息

1 Division of Critical Care, Department of Pediatrics, Riley Hospital for Children at Indiana University Health, Indiana University School of Medicine, Indianapolis, IN, USA.

2 Division of Cardiothoracic Surgery, Department of Surgery, Riley Hospital for Children at Indiana University Health, Indiana University School of Medicine, Indianapolis, IN, USA.

出版信息

World J Pediatr Congenit Heart Surg. 2019 Jul;10(4):400-406. doi: 10.1177/2150135119846040.

Abstract

BACKGROUND

Delayed sternal closure (DSC) following pediatric cardiac surgery is commonly implemented at many centers. Infectious complications occur in 18.7% of these patients based on recent multicenter data. We aimed to describe our experience with DSC, hypothesizing that our practices surrounding the implementation and maintenance of the open sternum during DSC minimize the risk of infectious complications.

METHODS

We reviewed patients less than 365 days who underwent DSC between 2012 and 2016 at our institution. Infectious complications as defined by the Society of Thoracic Surgeons Congenital Heart Surgery Database were recorded. Patients with and without infectious complications were compared using Wilcoxon rank sum tests or Fisher exact tests as appropriate.

RESULTS

We identified 165 patients less than 365 days old who underwent DSC, 135 (82%) of whom had their skin closed over their open sternum. Median duration of open sternum was 3 days (range: 1-32 days). Infectious complications occurred in 15 (9.1%) patients-13 developed clinical sepsis with positive blood cultures, one patient developed ventilator-associated pneumonia, and one patient developed wound infection (0.6%). No cases of mediastinitis occurred. No statistical differences in characteristics between patients with and without infectious complications could be identified.

CONCLUSION

Infectious complications after DSC at our institution were notably less than reported in recent literature, primarily due to minimization of surgical site infections. Practices described in the article, including closing skin over the open sternum whenever possible, could potentially aid other institutions aiming to reduce infectious complications associated with DSC.

摘要

背景

小儿心脏手术后延迟胸骨闭合(DSC)在许多中心普遍实施。根据最近的多中心数据,这些患者中有18.7%发生感染性并发症。我们旨在描述我们在DSC方面的经验,推测我们在DSC期间围绕开放胸骨的实施和维持的做法可将感染性并发症的风险降至最低。

方法

我们回顾了2012年至2016年在我们机构接受DSC的年龄小于365天的患者。记录了胸外科医师协会先天性心脏病手术数据库定义的感染性并发症。根据情况,使用Wilcoxon秩和检验或Fisher精确检验对有和没有感染性并发症的患者进行比较。

结果

我们确定了165例年龄小于365天接受DSC的患者,其中135例(82%)在开放胸骨上闭合了皮肤。开放胸骨的中位持续时间为3天(范围:1 - 32天)。15例(9.1%)患者发生感染性并发症——13例出现临床败血症且血培养阳性,1例患者发生呼吸机相关性肺炎,1例患者发生伤口感染(0.6%)。未发生纵隔炎病例。有和没有感染性并发症的患者在特征上未发现统计学差异。

结论

我们机构DSC后的感染性并发症明显低于最近文献报道,主要是由于手术部位感染的最小化。本文所述的做法,包括尽可能在开放胸骨上闭合皮肤,可能有助于其他旨在减少与DSC相关的感染性并发症的机构。

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