2012年至2017年期间，转诊至喀麦隆一家国家实验室的乙肝表面抗原阳性患者中抗丁型肝炎病毒抗体流行率的演变趋势。
Evolutionary trends in the prevalence of anti-HDV antibodies among patients positive for HBsAg referred to a national laboratory in Cameroon from 2012 to 2017.
作者信息
Noubissi-Jouegouo Laurence, Atsama Marie Amougou, Tagnouokam-Ngoupo Paul Alain, Monamele Chavely Gwladys, Ngono Laure, Njouom Richard
机构信息
Virology Department, Centre Pasteur of Cameroon, Po Box 1274, Yaoundé, Cameroon.
School of Health Sciences, Catholic University of Central Africa, Yaoundé, Cameroon.
出版信息
BMC Res Notes. 2019 Jul 15;12(1):417. doi: 10.1186/s13104-019-4460-4.
OBJECTIVE
The aim of this study was to update the data on the prevalence of anti-HDV antibodies in Cameroon.
RESULTS
Antibodies against hepatitis Delta virus (Anti-HDV) were found in 16.48% (95% CI 11.46-18.77%) of 426 hepatitis B virus surface antigen positive patients in Cameroon. Remarkably, they were significantly higher among people over 40 years and those living in the East and South regions of Cameroon at 66.7%, 50%, and 40%, respectively. These results suggest that older age and living in areas in the dense forest may be risk factors for Hepatitis D infection.
目的
本研究的目的是更新喀麦隆抗HDV抗体流行率的数据。
结果
在喀麦隆426例乙肝病毒表面抗原阳性患者中，16.48%（95%置信区间11.46 - 18.77%）的患者检测出抗丁型肝炎病毒（抗HDV）抗体。值得注意的是，在40岁以上人群以及居住在喀麦隆东部和南部地区的人群中，抗HDV抗体阳性率显著更高，分别为66.7%、50%和40%。这些结果表明，年龄较大以及生活在茂密森林地区可能是丁型肝炎感染的危险因素。
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