Gyulai F, Baran M
Institute of Animal Physiology, Slovak Academy of Sciences, Kosice, Czechoslovakia.
Arch Tierernahr. 1988 Feb;38(2):153-7. doi: 10.1080/17450398809425393.
In a first experiment 4 rams consumed over a period of 70 days 0; 82; 208 and 345 mg of monensin daily, respectively. All doses of monensin caused a marked decrease in total numbers of rumen protozoa in samples taken after this period. More than 90% of total protozoal numbers belonged to the genus Entodinium. The sensitivity of the genus Entodinium to monensin was found to be lower than that of genera Dasytricha and Isotricha. In the second experiment 24 lambs were fed hay and concentrates in the ratio 60:40% (groups 1 and 2) and 40:60% (groups 3 and 4). Groups 2 and 4 received 40 mg monensin per animal daily during 16 weeks. The decrease in protozoal numbers due to monensin in samples taken after this period was significant (P less than 0.001) in lambs fed the concentrate diet (groups 3 and 4) and also in lambs from groups 1 and 2 fed the roughage diet (P less than 0.05). The statistical evaluation of the inhibition of total protozoal numbers by monensin (%) in lambs fed both diets has shown that the antiprotozoal effect of monensin was significantly more intensive with the concentrate diet (P less than 0.025) than with the roughage diet.
在第一个实验中，4只公羊在70天的时间里，分别每日摄入0、82、208和345毫克莫能菌素。在此期间结束后采集的样本中，所有剂量的莫能菌素均使瘤胃原虫总数显著减少。原虫总数的90%以上属于内毛虫属。研究发现，内毛虫属对莫能菌素的敏感性低于双毛虫属和等毛虫属。在第二个实验中，24只羔羊分别按60:40%（第1组和第2组）和40:60%（第3组和第4组）的比例饲喂干草和精饲料。第2组和第4组在16周内每只动物每日接受40毫克莫能菌素。在此期间结束后采集的样本中，饲喂精饲料的羔羊（第3组和第4组）以及饲喂粗饲料的第1组和第2组羔羊中，莫能菌素导致的原虫数量减少均具有显著性（P小于0.001）（P小于0.05）。对两种日粮饲喂的羔羊中莫能菌素对原虫总数的抑制率（%）进行统计评估表明，莫能菌素对精饲料日粮的抗原虫作用（P小于0.025）显著强于粗饲料日粮。
