Carlier Laurence, Muller Jan, Debaveye Yves, Verelst Sandra, Rex Steffen
Department of Anesthesiology, University Hospitals Leuven, Leuven, Belgium.
Department of Emergency Medicine, University Hospitals Leuven, Leuven, Belgium.
Turk J Emerg Med. 2019 May 15;19(3):111-112. doi: 10.1016/j.tjem.2019.04.003. eCollection 2019 Jul.
Around 0.1-0.2% of all pregnancies are complicated by respiratory failure. The altered physiology of pregnancy predisposes mother and child to develop hypoxia and respiratory failure more easily than a non-pregnant patient. Respiratory failure in pregnancy may have detrimental fetal complications, therefore extensive knowledge of the range of therapeutic options is necessary. If conventional lung-protective mechanical ventilation strategies fail, alternative approaches such as veno-venous extracorporeal membrane oxygenation (VV-ECMO) should be considered.
A previously healthy 30-year-old P1G2 at 26 weeks and 6 days of gestation was admitted to the emergency department because of a severe respiratory infection. She suffered of severe hypoxic respiratory failure due to an overwhelming pneumonia (influenza type A) with acute respiratory distress syndrome (ARDS). Because long protective ventilation strategies and ventilation in prone positioning were inadequate, and further respiratory deterioration occurred, VV-ECMO was initiated.
In a pregnant patient with severe respiratory failure, when other interventions fail, initiation of VV-ECMO should not be delayed. The use of VV-ECMO in pregnancy is a multi-disciplinary team approach.
约0.1 - 0.2%的妊娠会并发呼吸衰竭。妊娠时生理状态的改变使母婴比非妊娠患者更容易发生缺氧和呼吸衰竭。妊娠合并呼吸衰竭可能会对胎儿产生有害并发症,因此有必要广泛了解各种治疗选择。如果传统的肺保护性机械通气策略失败,应考虑采用诸如静脉 - 静脉体外膜肺氧合(VV - ECMO)等替代方法。
一名既往健康的30岁孕妇,孕1产0,孕26周6天,因严重呼吸道感染入住急诊科。她因甲型流感所致的重症肺炎合并急性呼吸窘迫综合征(ARDS)而出现严重的低氧性呼吸衰竭。由于长时间的肺保护性通气策略及俯卧位通气效果不佳,且呼吸状况进一步恶化,遂启动VV - ECMO治疗。
对于患有严重呼吸衰竭的孕妇,当其他干预措施失败时,不应延迟启动VV - ECMO。妊娠患者使用VV - ECMO需要多学科团队协作。