Lund University, Lund, Sweden.
Lund University, Lund, Sweden, and Better Management of Patients With Osteoarthritis Registry, Gothenburg, Sweden.
Arthritis Care Res (Hoboken). 2020 Feb;72(2):201-207. doi: 10.1002/acr.24033. Epub 2020 Jan 9.
To compare the effectiveness of education (ED) plus home exercise (HE) and ED plus supervised exercise (SE) according to information provided by the Better Management of Patients With Osteoarthritis (BOA) Registry, a nationally implemented rehabilitation program for patients with hip and knee osteoarthritis (OA). In addition, we investigated whether or not the effect of the treatments differed based on the joint affected by OA (hip versus knee).
We included 38,030 participants from the BOA Registry with knee or hip OA who were treated with either ED, HE, or SE. The effect of the 3 treatment options on the pain intensity reduction (range 0-10) immediately postintervention and at 12 months was estimated using a mixed-effects model adjusted for age, sex, body mass index, affected joint (hip or knee), pain at baseline, comorbidity, and level of education.
The participants undergoing HE or SE experienced a greater pain reduction compared to participants who received ED, both after the treatment (group mean change for ED -0.91 [95% confidence interval (95% CI) -1.15, -0.68], for HE -1.06 [95% CI -1.10, -1.01], and for SE -1.12 [95% CI -1.15, -1.08]) and at 12 months (group mean change for ED -0.58 [95% CI -0.87, -0.30], for HE -0.82 [95% CI -0.87, -0.76], and for SE -0.82 [95% CI -0.86, -0.77]). Patients with knee OA who underwent HE or SE improved more compared to patients with hip OA at both follow-ups.
In primary care, HE and SE lead to similar reductions in pain intensity but are more effective than ED alone. In addition, people with knee OA benefit more from HE and SE than people with hip OA.
通过 Better Management of Patients With Osteoarthritis(BOA)登记处提供的信息,比较教育(ED)加家庭运动(HE)与 ED 加监督运动(SE)的有效性,该登记处是一个针对髋和膝关节骨关节炎(OA)患者的全国性康复计划。此外,我们还研究了治疗效果是否因受 OA 影响的关节(髋或膝)而不同。
我们纳入了来自 BOA 登记处的 38030 名患有膝或髋 OA 的患者,他们分别接受 ED、HE 或 SE 治疗。使用混合效应模型,根据年龄、性别、体重指数、受影响的关节(髋或膝)、基线时的疼痛、合并症和教育水平,调整模型后,估计 3 种治疗选择对干预即刻和 12 个月时疼痛强度降低的影响(范围 0-10)。
与接受 ED 治疗的患者相比,接受 HE 或 SE 治疗的患者在治疗后(ED 组平均变化-0.91[95%置信区间(95%CI)-1.15,-0.68],HE 组-1.06[95%CI-1.10,-1.01],SE 组-1.12[95%CI-1.15,-1.08])和 12 个月时(ED 组平均变化-0.58[95%CI-0.87,-0.30],HE 组-0.82[95%CI-0.87,-0.76],SE 组-0.82[95%CI-0.86,-0.77])的疼痛减轻程度更大。在两次随访中,接受 HE 或 SE 的膝 OA 患者比髋 OA 患者改善更明显。
在初级保健中,HE 和 SE 可使疼痛强度降低程度相似,但比单独 ED 更有效。此外,膝 OA 患者从 HE 和 SE 中获益多于髋 OA 患者。