Jun Joo Hyun, Kang Min-Kyung, Hyeon Joon-Sang, Choi Eunha, Kim Youngrok, Kim Ki Seok, Chung Mi Hwa, Jun In-Jung
Department of Anesthesiology and Pain Medicine, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, 948-1, Daerim 1-dong, Yeongdeungpo-gu, Seoul, 150-950, South Korea.
Department of Cardiology, Kangnam Sacred Heart Hospital, Hallym University Medical Center, Seoul, South Korea.
J Cardiothorac Surg. 2019 Jul 22;14(1):140. doi: 10.1186/s13019-019-0964-1.
Atrial septal defect (ASD) is a congenital cardiac defect often diagnosed in adult patients. Mitral regurgitation (MR) observed in ASD patients mostly improves after ASD closure. However, a subset of adult ASD patients present new-onset MR or aggravation of preexisting MR after ASD closure. Intraoperative MR aggravation after surgical ASD closure is a rare occurrence which has not been reported in the literature to date.
A 54-year-old woman was referred to our center due to large secundum ASD with a diameter of 17 mm which was incidentally detected on pre-operative echocardiography at a local clinic. Surgical repair of ASD under mini-thoracotomy was performed. After completion of the operation, intra-operative transesophageal echocardiography showed newly developed Grade II MR which subsequently deteriorated to severe level on postoperative day 3. Because the patient was asymptomatic, we decided to observe closely and treat conservatively with diuretics. Thereafter, echocardiography was evaluated on postoperative day 10 and MR disappeared to trivial level.
Intraoperative MR aggravation is a rare complication following ASD closure. The possibility of MR aggravation should be evaluated in all ASD patients prior to surgery. This case highlights the importance of mitral leaflet examination after ASD closure for early detection of MR.
房间隔缺损(ASD)是一种常于成年患者中被诊断出的先天性心脏缺陷。在房间隔缺损患者中观察到的二尖瓣反流(MR)在房间隔缺损闭合后大多会改善。然而,一部分成年房间隔缺损患者在房间隔缺损闭合后出现新发二尖瓣反流或原有二尖瓣反流加重。手术闭合房间隔缺损后术中二尖瓣反流加重是一种罕见情况,迄今为止文献中尚未有报道。
一名54岁女性因直径17毫米的继发孔型大房间隔缺损被转诊至我院,该缺损在当地诊所术前超声心动图检查时偶然发现。在小切口开胸下行房间隔缺损手术修复。手术完成后,术中经食管超声心动图显示新出现的二级二尖瓣反流,随后在术后第3天恶化至重度。由于患者无症状,我们决定密切观察并使用利尿剂进行保守治疗。此后,在术后第10天进行超声心动图评估,二尖瓣反流消失至微量水平。
术中二尖瓣反流加重是房间隔缺损闭合后一种罕见的并发症。在所有房间隔缺损患者手术前均应评估二尖瓣反流加重的可能性。本病例强调了房间隔缺损闭合后二尖瓣叶检查对于早期发现二尖瓣反流的重要性。