全国退伍军人非贲门胃腺癌队列中幽门螺杆菌感染的血清流行率。
Seroprevalence of Helicobacter pylori Infection in a National Cohort of Veterans With Noncardia Gastric Adenocarcinoma.
机构信息
Division of Gastroenterology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.
Division of Gastroenterology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.
出版信息
Clin Gastroenterol Hepatol. 2020 May;18(5):1235-1237.e1. doi: 10.1016/j.cgh.2019.07.026. Epub 2019 Jul 20.
Abstract
Conventional teaching is that Helicobacter pylori infection is required for the development of non-cardia gastric adenocarcinoma (NCGC) through a sequence of atrophic gastritis, intestinal metaplasia, dysplasia, and finally, cancer. However, studies have not demonstrated a 100% rate of H pylori infection in gastric malignancy, hypothesized to be due to false negatives, gastric atrophy leading to apparent loss of infection, and inclusion of cardia, nonintestinal cancers..
摘要
传统观点认为，幽门螺杆菌（Helicobacter pylori，H.pylori）感染是导致非贲门胃腺癌（non-cardia gastric adenocarcinoma，NCGC）发生的必要条件，其发展过程依次为萎缩性胃炎、肠化生、异型增生，最终进展为癌症。然而，研究并未在所有胃恶性肿瘤中均发现 100%的 H.pylori 感染率，这被认为是由于假阴性、胃萎缩导致的明显感染丢失以及贲门、非肠型癌症的包含等因素所致。
相似文献
1
Seroprevalence of Helicobacter pylori Infection in a National Cohort of Veterans With Noncardia Gastric Adenocarcinoma.
Clin Gastroenterol Hepatol. 2020 May;18(5):1235-1237.e1. doi: 10.1016/j.cgh.2019.07.026. Epub 2019 Jul 20.
2
Opposing risks of gastric cardia and noncardia gastric adenocarcinomas associated with Helicobacter pylori seropositivity.
J Natl Cancer Inst. 2006 Oct 18;98(20):1445-52. doi: 10.1093/jnci/djj393.
3
Two distinct aetiologies of cardia cancer; evidence from premorbid serological markers of gastric atrophy and Helicobacter pylori status.
Gut. 2007 Jul;56(7):918-25. doi: 10.1136/gut.2006.114504. Epub 2007 Feb 22.
4
Prevalence of Helicobacter pylori Positive Non-cardia Gastric Adenocarcinoma Is Low and Decreasing in a US Population.
Dig Dis Sci. 2020 Aug;65(8):2403-2411. doi: 10.1007/s10620-019-05955-2. Epub 2019 Nov 14.
5
Association of adenocarcinomas of the distal esophagus, "gastroesophageal junction," and "gastric cardia" with gastric pathology.
Am J Surg Pathol. 2010 Oct;34(10):1521-7. doi: 10.1097/PAS.0b013e3181eff133.
6
Helicobacter pylori infection and gastric atrophy: risk of adenocarcinoma and squamous-cell carcinoma of the esophagus and adenocarcinoma of the gastric cardia.
J Natl Cancer Inst. 2004 Mar 3;96(5):388-96. doi: 10.1093/jnci/djh057.
7
The relative and attributable risks of cardia and non-cardia gastric cancer associated with Helicobacter pylori infection in China: a case-cohort study.
Lancet Public Health. 2021 Dec;6(12):e888-e896. doi: 10.1016/S2468-2667(21)00164-X.
8
Antral-type mucosa in the gastric incisura, body, and fundus (antralization): a link between Helicobacter pylori infection and intestinal metaplasia?
Am J Gastroenterol. 2000 Jan;95(1):114-21. doi: 10.1111/j.1572-0241.2000.01609.x.
9
Helicobacter pylori infection, chronic atrophic gastritis and risk of stomach and esophagus cancer: Results from the prospective population-based ESTHER cohort study.
Int J Cancer. 2020 May 15;146(10):2773-2783. doi: 10.1002/ijc.32610. Epub 2019 Aug 29.
10
Relationship between body mass index and the risk of early gastric cancer and dysplasia regardless of Helicobacter pylori infection.
Gastric Cancer. 2015 Oct;18(4):762-73. doi: 10.1007/s10120-014-0429-0. Epub 2014 Sep 21.
引用本文的文献
1
Inverse Association Between Gluteofemoral Obesity and Risk of Non-Cardia Gastric Intestinal Metaplasia.
Clin Gastroenterol Hepatol. 2023 Jan;21(1):64-71. doi: 10.1016/j.cgh.2022.04.033. Epub 2022 May 13.
2
Databases for Gastrointestinal Clinical and Public Health Research: Have Database, Will Research.
Gastroenterology. 2022 Jul;163(1):31-34. doi: 10.1053/j.gastro.2022.04.024. Epub 2022 Apr 27.
3
Follow-up analysis and histopathological study of gastric mucosa in patients with infection.
J Int Med Res. 2021 Dec;49(12):3000605211055397. doi: 10.1177/03000605211055397.
4
The association of with pancreatic cancer.
GastroHep. 2020 Jul;2(4):157-164. doi: 10.1002/ygh2.398. Epub 2020 May 5.
5
Low Rates of Retesting for Eradication of Helicobacter pylori Infection After Treatment in the Veterans Health Administration.
Clin Gastroenterol Hepatol. 2021 Feb;19(2):305-313.e1. doi: 10.1016/j.cgh.2020.03.059. Epub 2020 Apr 6.
6
Risk Factors and Incidence of Gastric Cancer After Detection of Helicobacter pylori Infection: A Large Cohort Study.
Gastroenterology. 2020 Feb;158(3):527-536.e7. doi: 10.1053/j.gastro.2019.10.019. Epub 2019 Oct 22.
本文引用的文献
1
Infection.
N Engl J Med. 2019 Mar 21;380(12):1158-1165. doi: 10.1056/NEJMcp1710945.
2
Cancer Incidence Among Patients of the U.S. Veterans Affairs Health Care System: 2010 Update.
Mil Med. 2017 Jul;182(7):e1883-e1891. doi: 10.7205/MILMED-D-16-00371.
3
The Clinical Evidence Linking to Gastric Cancer.
Cell Mol Gastroenterol Hepatol. 2016 Dec 27;3(2):183-191. doi: 10.1016/j.jcmgh.2016.12.001. eCollection 2017 Mar.
4
Must-Have Knowledge about the Helicobacter pylori-Negative Gastric Cancer.
Gut Liver. 2016 Mar;10(2):157-9. doi: 10.5009/gnl16002.
5
Gastric cancer and Helicobacter pylori: a combined analysis of 12 case control studies nested within prospective cohorts.
Gut. 2001 Sep;49(3):347-53. doi: 10.1136/gut.49.3.347.
6
Helicobacter pylori and gastric carcinogenesis.
Am J Surg Pathol. 1995;19 Suppl 1:S37-43.
7
Helicobacter pylori infection and gastric carcinoma among Japanese Americans in Hawaii.
N Engl J Med. 1991 Oct 17;325(16):1132-6. doi: 10.1056/NEJM199110173251604.
8
Helicobacter pylori infection and the risk of gastric carcinoma.
N Engl J Med. 1991 Oct 17;325(16):1127-31. doi: 10.1056/NEJM199110173251603.
Zotero 插件