Yoshida Takeichi, Yamashita Yasunobu, Kitano Masayuki
Department of Gastroenterology, Wakayama Medical University, 811-1 Kimiidera, Wakayama-city, Wakayama 641-0012, Japan.
Diagnostics (Basel). 2019 Jul 24;9(3):81. doi: 10.3390/diagnostics9030081.
Detection of small pancreatic cancers, which have a better prognosis than large cancers, is needed to reduce high mortality rates. Endoscopic ultrasound (EUS) is the most sensitive imaging modality for detecting pancreatic lesions. The high resolution of EUS makes it particularly useful for detecting small pancreatic lesions that may be missed by other imaging modalities. Therefore, EUS should be performed in patients with obstructive jaundice in whom computed tomography (CT) or magnetic resonance imaging (MRI) does not identify a definite pancreatic lesion. Interest in the use of EUS for screening individuals at high risk of pancreatic cancer, including those with intraductal papillary mucinous neoplasms (IPMNs) and familial pancreatic cancer is growing. Contrast-enhanced EUS can facilitate differential diagnosis of small solid pancreatic lesions as well as malignant cystic lesions. In addition, EUS-guided fine needle aspiration can provide samples of small pancreatic lesions. Thus, EUS and EUS-related techniques are essential for early diagnosis of pancreatic cancer.
为降低高死亡率，需要检测小胰腺癌，其预后比大癌更好。内镜超声（EUS）是检测胰腺病变最敏感的成像方式。EUS的高分辨率使其对于检测其他成像方式可能遗漏的小胰腺病变特别有用。因此，对于计算机断层扫描（CT）或磁共振成像（MRI）未发现明确胰腺病变的梗阻性黄疸患者，应进行EUS检查。对使用EUS筛查胰腺癌高危个体（包括导管内乳头状黏液性肿瘤（IPMN）患者和家族性胰腺癌患者）的兴趣正在增加。对比增强EUS有助于小实性胰腺病变以及恶性囊性病变的鉴别诊断。此外，EUS引导下细针穿刺可提供小胰腺病变的样本。因此，EUS及与EUS相关的技术对于胰腺癌的早期诊断至关重要。
