Department of Oral Surgery, Bonn University Dental Clinic, Bonn, Germany.
Acta Odontol Scand. 2020 Jan;78(1):31-37. doi: 10.1080/00016357.2019.1645353. Epub 2019 Jul 26.
To determine the baseline perfusion parameters of the alveolar mucosa using laser Doppler flowmetry and tissue spectrophotometry (LDF-TS) in healthy adults. Forty-two healthy adult subjects of either sex were tested. The perfusion of the alveolar mucosa was evaluated using a laser Doppler flowmetry and tissue spectrophotometry using O2C 'oxygen to see' device. The measurements encompassed the maxillary and mandibular mucosa at 20 different points. The O2C device is a reliable method for noninvasive measurement of different perfusion parameters of the oral mucosa. The hemoglobin saturation values (So2 in %), as well as relative amount of hemoglobin in arbitrary units (AU) of the maxillary mucosa demonstrated lower values of that in the mandible. The flow value (AU) exhibited a significant difference in the posterior molar region only, while the velocity value (AU) showed a significant difference across all points except for the anterior region. the present study provides a set of brand-new perfusion parameters of the microcirculation of the alveolar mucosa using LDF-TS. The study suggests a variation of the perfusion parameters between the maxilla and the mandible. Differences in the anatomy of the blood supply, the thickness of the mucosa and the cortical bone, may be attributed to this variation. Further studies using different probes and a combination of ultrasonic measurements and SDF imaging will aid in giving a better overview of the perfusion in the oral mucosa.
使用激光多普勒血流仪和组织分光光度法(LDF-TS)测定健康成年人肺泡黏膜的基础灌注参数。
共检测了 42 名健康成年受试者,无论性别。使用 O2C“氧气观察”设备的激光多普勒血流仪和组织分光光度法评估肺泡黏膜的灌注情况。测量了上颌和下颌黏膜的 20 个不同部位。O2C 设备是一种可靠的方法,可用于非侵入性测量口腔黏膜的不同灌注参数。上颌黏膜的血红蛋白饱和度值(So2%)和相对血红蛋白量(任意单位 AU)值均低于下颌。仅在后磨牙区的流量值(AU)存在显著差异,而除前牙区外,所有部位的速度值(AU)均存在显著差异。本研究提供了使用 LDF-TS 测定肺泡黏膜微循环的一组全新的灌注参数。研究表明,上颌和下颌的灌注参数存在差异。可能与这种差异有关的是血液供应的解剖结构、黏膜和皮质骨的厚度不同。使用不同的探头以及超声测量和 SDF 成像的组合进行进一步研究,将有助于更好地了解口腔黏膜的灌注情况。