Vàzquez R, Carvajal J F, Pèrez E, Carretero J, Riesco J M, Blanco E
Department of Morphological Sciences, University of Salamanca, Spain.
J Submicrosc Cytol Pathol. 1988 Apr;20(2):297-304.
The annular gap junctions in the cuboidal ependymocytes of the median eminence of rats were studied after intraventricular administration (3rd ventricle) of methysergide and thyrotropin releasing hormone. Isolated annular gap junctions were found in the ependymocytes of normal animals. In experimental rats an increase was observed in the number of annular gap junctions at 5 min after administration of the drugs; the increase was more apparent at 10 min postadministration. Likewise, the ependymocytes showed a clear development of the Golgi complex and an increase in the number of vesicles close to the lateral membranes. Accordingly, the increase observed in annular gap junctions could be interpreted as a sign of cellular activity indicative of a greater exchange of substances through the ependymocytes.
在向大鼠第三脑室脑室内注射麦角新碱和促甲状腺激素释放激素后，对大鼠正中隆起立方上皮细胞中的环状缝隙连接进行了研究。在正常动物的室管膜细胞中发现了孤立的环状缝隙连接。在实验大鼠中，给药后5分钟观察到环状缝隙连接数量增加；给药后10分钟增加更为明显。同样，室管膜细胞显示高尔基体复合体明显发育，靠近侧膜的囊泡数量增加。因此，观察到的环状缝隙连接增加可解释为细胞活动的标志，表明通过室管膜细胞的物质交换增加。
