Department of Psychology and Neuroscience, Dalhousie University, Life Sciences Centre, 1355 Oxford Street, PO BOX 15000, Halifax, Nova Scotia B3H 4R2, Canada.
Department of Psychiatry, University of Montreal, Ste. Justine Hospital, 3175 Chemin de la Côte-Sainte-Catherine, Montréal, Quebec H3T 1C4, Canada.
Addict Behav. 2019 Nov;98:106056. doi: 10.1016/j.addbeh.2019.106056. Epub 2019 Jul 17.
A mainstay treatment for opioid addiction in North America is methadone maintenance therapy (MMT) - a form of opiate agonist therapy (OAT). While efficacious for treating opioid addiction, MMT fails to address the concurrent polysubstance use that is common among opioid dependent clients. Moreover, psychosocial approaches for addressing polysubstance use during MMT are lacking. Our study's goals were to validate the use of the four-factor personality model of substance use vulnerability in MMT clients, and to demonstrate theoretically-relevant relationships of personality to concurrent substance use while receiving MMT.
Respondents included 138 daily-witnessed MMT clients (65.9% male, 79.7% Caucasian), mean age (SD) 40.18 (11.56), recruited across four Canadian MMT clinics. Bayesian confirmatory factor analysis was used to establish the structural validity of the four-factor personality model of substance use vulnerability (operationalized with the Substance Use Risk Profile Scale [SURPS]) in MMT clients. SURPS personality scores were then used as predictors for specific forms of recent (past 30-day) substance use.
Using a latent hierarchal model, hopelessness was associated with recent opioid use; anxiety sensitivity with recent tranquilizer use; and sensation seeking with recent alcohol, cannabis, and stimulant use.
Personality is associated with substance use patterns and may be an appropriate target for intervention for those undergoing MMT to reduce opioid use, and potentially dangerous concurrent use of other drugs, while receiving methadone.
在北美,阿片类药物成瘾的主要治疗方法是美沙酮维持治疗(MMT)——一种阿片类激动剂治疗(OAT)。虽然美沙酮维持治疗对治疗阿片类药物成瘾有效,但它无法解决阿片类药物依赖患者常见的同时使用多种药物的问题。此外,在接受美沙酮维持治疗期间,针对多药物使用的心理社会方法也很缺乏。我们的研究目的是验证物质使用脆弱性的四因素人格模型在美沙酮维持治疗患者中的应用,并证明人格与接受美沙酮维持治疗期间同时使用物质之间存在理论相关的关系。
研究对象包括 138 名每日观察的美沙酮维持治疗患者(65.9%为男性,79.7%为白种人),平均年龄(标准差)为 40.18(11.56),来自加拿大四个美沙酮维持治疗诊所。使用贝叶斯验证性因子分析来建立物质使用脆弱性的四因素人格模型(通过物质使用风险特征量表[SURPS]操作化)在美沙酮维持治疗患者中的结构有效性。然后,将 SURPS 人格得分用作近期(过去 30 天)物质使用的特定形式的预测因子。
使用潜在层次模型,绝望感与近期阿片类药物使用有关;焦虑敏感性与近期镇静剂使用有关;感觉寻求与近期酒精、大麻和兴奋剂使用有关。
人格与物质使用模式相关,可能是接受美沙酮维持治疗的患者的一个适当干预目标,以减少阿片类药物使用,并潜在地减少同时使用其他危险药物。