Chindamo Maria Chiara, Marques Marcos Arêas
Universidade Federal do Rio de Janeiro - UFRJ, Departamento de Clínica Médica, Rio de Janeiro, RJ, Brasil.
Rede D'Or São Luiz, Hospital Barra D'Or, Serviço de Clínica Médica, Rio de Janeiro, RJ, Brasil.
J Vasc Bras. 2019 Jun 25;18:e20180107. doi: 10.1590/1677-5449.180107.
Venous thromboembolism (VTE) encompasses the spectrum of manifestations of deep venous thrombosis and/or pulmonary embolism and is a common, serious, and preventable complication in hospitalized patients. Although immobility plays an important role in determining VTE risk in medical patients, no clear and uniform criteria exist to guide clinicians in assessing immobility. The variation in the descriptions that do exist makes it difficult to interpret and compare the results of randomized clinical trials with respect to the influence of different levels of immobility on the magnitude of VTE risk and the role that early ambulation as an isolated factor plays in prevention of such events. Understanding these limitations is a prerequisite for the proper use and interpretation of VTE risk assessment tools and for indicating the best strategy for preventing venous thrombosis in hospitalized medical patients. The objective of this study was to review the main evidence reported in the literature on the role of ambulation in prevention of VTE.
静脉血栓栓塞症（VTE）涵盖了深静脉血栓形成和/或肺栓塞的一系列表现，是住院患者常见、严重且可预防的并发症。尽管活动减少在确定内科患者VTE风险方面起着重要作用，但目前尚无明确统一的标准来指导临床医生评估活动减少情况。现有描述的差异使得难以解读和比较随机临床试验关于不同程度活动减少对VTE风险大小的影响以及早期活动作为独立因素在预防此类事件中所起作用的结果。了解这些局限性是正确使用和解读VTE风险评估工具以及指明预防住院内科患者静脉血栓形成最佳策略的先决条件。本研究的目的是回顾文献中报道的关于活动在预防VTE中作用的主要证据。
