Department of Radiology, Boston Medical Center, 820 Harrison Ave, FGH Building, 3rd Floor, Boston, MA, 02118, USA.
Ochsner Clinic Foundation, 1514 Jefferson Hwy, New Orleans, LA, 70121, USA.
Abdom Radiol (NY). 2020 Feb;45(2):307-311. doi: 10.1007/s00261-019-02151-8.
To compare CT angiography (CTA) and tagged red blood cell (RBC) scan as a function of time from these initial imaging studies to subsequent conventional angiography and catheter-directed embolization in patients with gastrointestinal (GI) bleeding.
An IRB-approved retrospective study was conducted of 35 consecutive patients diagnosed with GI bleeding that received angiography for planned catheter-directed embolization. Of these patients, 20 were diagnosed with bleeding using a tagged RBC scan, whereas 15 were diagnosed using CTA. The lengths of time between diagnostic study order to study completion, diagnostic study completion to angiography, and total time from diagnostic study order to angiography were calculated. The results of both groups were compared using a t test with p value of < 0.05 considered statistically significant.
The mean time from diagnostic study order to study completion was 3 h and 4 min for the CTA group and 5 h and 1 min for the tagged RBC scan group (p value = 0.0001). There was no statistically significant difference between the time to angiography after completion of the preceding diagnostic study. The total mean time from diagnostic study order to intervention was 6 h and 8 min for the CTA group and 9 h and 29 min for the tagged RBC scan group, a statistically significant difference (p value = 0.028).
In patients requiring conventional angiography for GI bleeding, CT angiography results in a faster time to angiography than tagged RBC scan, which appears to be due to the longer duration required to complete the tagged RBC scan. Decreasing time to angiography is vital, as GI bleeding can be fatal and earlier diagnosis and intervention has the potential to reduce morbidity and mortality, while also increasing sensitivity of angiography. These findings may assist ordering clinicians in deciding on the appropriate diagnostic study.
比较 CT 血管造影 (CTA) 和标记红细胞 (RBC) 扫描作为初始影像学研究与随后的常规血管造影和导管引导栓塞在胃肠道 (GI) 出血患者中的时间函数。
对 35 例连续诊断为 GI 出血并接受血管造影计划导管引导栓塞的患者进行了一项经机构审查委员会批准的回顾性研究。这些患者中,20 例使用标记 RBC 扫描诊断为出血,而 15 例使用 CTA 诊断为出血。计算了从诊断性研究命令到研究完成、诊断性研究完成到血管造影以及从诊断性研究命令到血管造影的总时间。使用 t 检验比较两组结果,p 值<0.05 被认为具有统计学意义。
CTA 组从诊断性研究命令到研究完成的平均时间为 3 小时 4 分钟,标记 RBC 扫描组为 5 小时 1 分钟(p 值=0.0001)。完成前一个诊断性研究后进行血管造影的时间没有统计学差异。从诊断性研究命令到干预的总平均时间为 CTA 组 6 小时 8 分钟,标记 RBC 扫描组 9 小时 29 分钟,存在统计学差异(p 值=0.028)。
在需要常规血管造影治疗 GI 出血的患者中,CTA 导致血管造影的时间比标记 RBC 扫描更快,这似乎是由于完成标记 RBC 扫描所需的时间更长。缩短血管造影时间至关重要,因为 GI 出血可能是致命的,早期诊断和干预有可能降低发病率和死亡率,同时提高血管造影的敏感性。这些发现可能有助于临床医生选择适当的诊断性研究。