Regional Esophahagogastric Centre, Department of Upper Gastrointestinal Surgery, Broomfield Hospital, Mid Essex Hospital Services NHS Trust, Chelmsford, U.K.
Department of Surgery, 424 General Military Hospital, Thessaloniki, Greece.
Anticancer Res. 2019 Aug;39(8):4291-4295. doi: 10.21873/anticanres.13594.
BACKGROUND/AIM: Surgical resection for esophageal cancer has remained the gold-standard therapy provided worldwide. Subcarinal lymph-nodes are classified as peri-esophageal nodes and their dissection may be performed during a 2- or 3-stage esophagectomy. The necessity and prognostic value of subcarinal lymphadenectomy is still debatable. The purpose of this study was to investigate the rate of invaded subcarinal lymph-nodes out of the total lymph-nodes resected. Detection of invaded nodes was correlated with clinical staging and tumor differentiation.
This is a retrospective analysis of consecutive esophagectomies for cancer, performed in a UK tertiary center. The study was conducted over a 3-year period.
The rate of subcarinal lymph-node invasion was extremely low according to the results of our analysis.
Lymphadenectomy is not devoid of clinical impact on patients and therefore, the decision should actually be the outcome of a dynamic balance between complications and survival benefit.
背景/目的：手术切除仍然是全世界范围内治疗食管癌的金标准。隆突下淋巴结被归类为食管旁淋巴结，在二或三阶段食管癌切除术期间可进行清扫。隆突下淋巴结清扫术的必要性和预后价值仍存在争议。本研究旨在调查切除的总淋巴结中受累隆突下淋巴结的比例。受累淋巴结的检出与临床分期和肿瘤分化相关。
这是对英国一家三级中心连续进行的食管癌切除术的回顾性分析。该研究持续了 3 年。
根据我们的分析结果，隆突下淋巴结受侵的比例极低。
淋巴结清扫术确实对患者的临床有影响，因此，这一决策实际上应该是在并发症和生存获益之间进行动态平衡的结果。
