Department of Clinical Psychophysiology, Institute of Psychobiology, University of Trier, Johanniterufer 15, D-54290 Trier, Germany; Department of Engineering, University of Applied Sciences, Schneidershof, D-54293 Trier, Germany.
Department of Clinical Psychophysiology, Institute of Psychobiology, University of Trier, Johanniterufer 15, D-54290 Trier, Germany; Department of Engineering, University of Applied Sciences, Schneidershof, D-54293 Trier, Germany.
Biol Psychol. 2019 Nov;148:107729. doi: 10.1016/j.biopsycho.2019.107729. Epub 2019 Jul 29.
When studying the factors which influence stress reactivity in within-subject designs, test-retest reproducibility data is needed to estimate power and sample size. We report such data regarding a new experimental stress protocol, based on simultaneous application of the socially evaluated, bilateral feet Cold Pressor Test (CPT) and the Paced Auditory Serial Addition Task (PASAT). Cardiovascular, neuroendocrine, and subjective (affective) stress responses of 32 healthy males were measured twice, at an interval of one week. The novel protocol induced substantial stress reactivity in all parameters at both test and retest. Cardiovascular reactivity remained unchanged, but cortisol and subjective responses were lower at second stress exposure, with high test-retest stability of neuroendocrine (r>.7) and cardiovascular measures (r = .5 to r = .9). PASAT performance improved. Response attenuation suggests habituation-like and/or learning effects. Data provided by our study demonstrate feasibility and power of this stress protocol for investigating changes in stress reactivity in repeated, within-subject designs.
在研究影响个体内设计中应激反应的因素时，需要测试-再测试可重复性数据来估计功效和样本量。我们报告了一种新的实验性应激方案的相关数据，该方案基于同时应用社会评价的双侧足部冷加压试验（CPT）和 paced auditory serial addition task（PASAT）。我们两次测量了 32 名健康男性的心血管、神经内分泌和主观（情感）应激反应，两次测量之间间隔一周。在两次测试中，新方案都在所有参数上引起了明显的应激反应。心血管反应保持不变，但皮质醇和主观反应在第二次应激时较低，神经内分泌（r>.7）和心血管测量（r=.5 到 r=.9）具有很高的测试-再测试稳定性。PASAT 表现有所提高。反应衰减表明存在习惯化和/或学习效应。我们的研究提供的数据证明了这种应激方案在重复个体内设计中研究应激反应变化的可行性和功效。
