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特刊“加合物组学:阐明疾病的环境病因”

Special Issue "Adductomics: Elucidating the Environmental Causes of Disease".

作者信息

Pereira Sofia A, Antunes Alexandra M M

机构信息

CEDOC, Chronic Diseases Research Centre, NOVA Medical School, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, 1169-006 Lisboa, Portugal.

Centro de Química Estrutural, Instituto Superior Técnico, ULisboa, 1049-001 Lisboa, Portugal.

出版信息

High Throughput. 2019 Jul 31;8(3):17. doi: 10.3390/ht8030017.

Abstract

Adductomics studies represent effective tools for better understand how exposure to exogenous and endogenous reactive chemical agents underlie mechanism of diseases. This special issue is focused not only on summarizing the analytical methodologies used for DNA, protein, and mercapturic acid adductomics tools but also on highlighting the opportunities and challenges for the application of this type of studies in biomedical research.

摘要

加合物组学研究是深入了解接触外源性和内源性活性化学物质如何成为疾病发病机制基础的有效工具。本期特刊不仅聚焦于总结用于DNA、蛋白质和巯基尿酸加合物组学工具的分析方法,还着重强调这类研究在生物医学研究中的应用机遇与挑战。

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