失眠的精准医学

Precision Medicine for Insomnia.

作者信息

Boland Elaine, Goldschmied Jennifer, Kayser Matthew S, Gehrman Philip R

机构信息

Department of Psychiatry, Perelman School of Medicine of the University of Pennsylvania, 3535 Market Street, Suite 670, Philadelphia, PA 19104, USA; Michael J. Crescenz VA Medical Center, MIRECC, 2nd Floor, B229 3900 Woodland Ave., Philadelphia, PA 19104, USA.

Department of Psychiatry, Perelman School of Medicine of the University of Pennsylvania, 3535 Market Street, Suite 670, Philadelphia, PA 19104, USA.

出版信息

Sleep Med Clin. 2019 Sep;14(3):291-299. doi: 10.1016/j.jsmc.2019.04.001. Epub 2019 Jun 5.

DOI:10.1016/j.jsmc.2019.04.001

PMID:31375199

Abstract

Insomnia affects up to 15% of the US population. There are effective pharmacologic and behavioral treatments for insomnia; however, there is often no one-size-fits-all intervention. This article discusses the leading behavioral treatment of insomnia, cognitive behavioral therapy for insomnia, and its ability to be tailored to an individual's specific symptoms. It then discusses pharmacologic options for treating insomnia, and offers some guidance on medication selection to enhance personalized care. In addition, it discusses how the current evidence base can help providers make choices between pharmacologic and behavioral treatments.

摘要

失眠影响着多达15%的美国人口。对于失眠有有效的药物和行为治疗方法；然而，通常没有一种适用于所有人的干预措施。本文讨论失眠的主要行为治疗方法——失眠认知行为疗法，以及它针对个体特定症状进行调整的能力。然后讨论治疗失眠的药物选择，并提供一些关于药物选择的指导以加强个性化护理。此外，还讨论了当前的证据基础如何帮助医疗服务提供者在药物治疗和行为治疗之间做出选择。