使用长短期记忆模型预测多动症患者的物质使用障碍
Predicting Substance Use Disorder in ADHD Patients using Long-Short Term Memory Model.
作者信息
Fouladvand Sajjad, Hankosky Emily R, Henderson Darren W, Bush Heather, Chen Jin, Dwoskin Linda P, Freeman Patricia R, Kantak Kathleen, Talbert Jeffery, Tao Shiqiang, Zhang Guo-Qiang
机构信息
Institute for Biomedical Informatics, University of Kentucky, Lexington, KY.
Department of Computer Science, University of Kentucky, Lexington, KY.
出版信息
2018 IEEE Int Conf Healthc Inform Workshop (2018). 2018 Jun;2018:49-50. doi: 10.1109/ICHI-W.2018.00014. Epub 2018 Jul 19.
About 20% of individuals with attention deficit hyperactivity disorder (ADHD) are first diagnosed during adolescence. While preclinical experiments suggest that adolescent-onset exposure to ADHD medication is an important factor in the development of substance use disorder (SUD) phenotypes in adulthood, the long-term impact of ADHD medication initiated during adolescence has been largely unexplored in humans. Our analysis of 11,624 adolescent ADHD patients in the Truven database indicates that temporal medication features are the important factors on the health consequences related to SUD and ADHD medication initiation during adolescence.
约20%的注意力缺陷多动障碍（ADHD）患者在青春期首次被诊断出来。虽然临床前实验表明，青春期开始接触ADHD药物是成年后物质使用障碍（SUD）表型发展的一个重要因素，但青春期开始使用ADHD药物的长期影响在人类中尚未得到充分研究。我们对Truven数据库中11624名青少年ADHD患者的分析表明，用药时间特征是与青春期开始使用SUD和ADHD药物相关的健康后果的重要因素。
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