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经皮穿刺抽吸治疗小儿幕上硬膜下积脓:尼日利亚某城市的一项结局研究

Infantile supratentorial subdural empyema managed by percutaneous aspiration: an outcome study in a Nigerian city.

作者信息

Kanu Okezie Obasi, Esezobor Christopher I, Ojo Omotayo A, Asoegwu Chinyere N, Nnoli Chinenye, Dawang Yusuf, Temiye Edamisan

机构信息

Neurosurgery Division, Department of Surgery, College of Medicine University of Lagos & Lagos University Teaching Hospital, Idi-Araba, Nigeria.

Department of Pediatrics, College of Medicine University of Lagos & Lagos University Teaching Hospital, Idi-Araba, Nigeria.

出版信息

Sudan J Paediatr. 2019;19(1):37-43. doi: 10.24911/SJP.106-1520470056.

Abstract

Subdural empyema (SDE), a common neurosurgical emergency in the developing countries, accounts for 15%-20% of localised paediatric intracranial infections. In regions where modern diagnostic tools are scarce and inaccessible, detection of SDE may be delayed with subsequent poor outcome. Percutaneous subdural aspiration in patients with open anterior fontanel may be the only surgical option in resource-poor regions of the world. This review focuses on the management outcome, including neurological outcome of these children. Clinical charts of children with SDE and treated by percutaneous subdural tap between February 2006 and August 2014 were reviewed. Demographic, clinical, radiological, bacteriological parameters and outcome data were analysed. Forty-five children with a mean age of 10.6 ± 6.2 months (range: 2-17 months) and followed up for a median duration of 16.4 months were included. The most frequent clinical features were enlarged head circumference, fever, focal neurologic deficits and altered level of consciousness. Diagnosis of SDE was confirmed using trans-fontanel ultrasound scan in 32 (71.1%) children, computerised tomography in 12 (26.7%) children and magnetic resonance imaging in one (2.2%) child. SDE was unilateral in 73.3% and bilateral in 26.7%. In 23 (51.1%) children with a positive culture, ( = 10), anaerobes ( = 7), and ( = 6 each) were the most common organisms. Forty-three children (95.6%) survived, 36 of which had good Glasgow outcome score. Seven children still had moderate deficits at 3 months. Treatment of SDE in young children with patent fontanel using percutaneous subdural tap has good therapeutic and neurological outcome.

摘要

硬膜下积脓(SDE)是发展中国家常见的神经外科急症,占小儿局限性颅内感染的15% - 20%。在缺乏现代诊断工具且难以获取的地区,SDE的诊断可能会延迟,进而导致不良后果。对于前囟未闭的患者,经皮硬膜下穿刺抽吸可能是世界上资源匮乏地区唯一的手术选择。本综述聚焦于这些儿童的治疗结果,包括神经学结果。回顾了2006年2月至2014年8月间接受经皮硬膜下穿刺治疗的SDE患儿的临床病历。分析了人口统计学、临床、放射学、细菌学参数及结果数据。纳入了45名平均年龄为10.6±6.2个月(范围:2 - 17个月)、中位随访时间为16.4个月的儿童。最常见的临床特征为头围增大、发热、局灶性神经功能缺损及意识水平改变。32名(71.1%)儿童通过经囟门超声扫描确诊SDE,12名(26.7%)儿童通过计算机断层扫描确诊,1名(2.2%)儿童通过磁共振成像确诊。SDE单侧发生的占73.3%,双侧发生的占26.7%。在23名(51.1%)培养结果阳性的儿童中,( = 10)、厌氧菌( = 7)以及 和 (各 = 6)是最常见的病原体。43名儿童(95.6%)存活,其中36名格拉斯哥预后评分良好。7名儿童在3个月时仍有中度功能缺损。对前囟未闭的幼儿采用经皮硬膜下穿刺治疗SDE具有良好的治疗效果和神经学结果。

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