Department of Geriatric, Cadre Ward, 947 Hospital of PLA, Kashgar Shule, Xinjiang 844200, China.
Department of Pharmaceutics and Instruments, 947 Hospital of PLA, Kashgar Shule, Xinjiang 844200, China.
J Infect Public Health. 2020 Feb;13(2):159-163. doi: 10.1016/j.jiph.2019.07.010. Epub 2019 Aug 3.
The NLC model in oncology setting was not well established in China, and there was no study evaluating the clinical effectiveness of NLC versus oncologist-led care (OLC) in Chinese patients with cancer. We therefore designed a pilot study to evaluate the clinical usefulness after NLC versus OLC in Chinese patients with cancer.
This pilot, single center, prospective study was designed to evaluate clinical effectiveness of NLC versus oncologist-led care (OLC) in Chinese patients with cancer. Adult patients of either gender (aged between 20 and 65 years) who were diagnosed with any cancer at China were included. The patients' with stage IV cancer or who were not willing to give written consent to participate in this study were excluded during screening phase of our study. We assessed the symptoms from each enrolled patients, the most common symptoms associated with any cancer patients are pain, dyspnea and constipation. Also distress symptoms (caused by pain and dyspnea) and low quality of life are seen in patients with advanced stage of cancer.
A total of 220 patients who were visited in our hospital for consultation were enrolled and assigned to nurse led care and oncologist led care group (110 patients in each group). Pain intensity, dyspnea intensity and constipation intensity was recorded for patients of nurse led care and oncologist led care group. Pain intensity, dyspnea intensity and constipation intensity on numerical rating scale was numerically lesser in Nurse led care group as compared to oncologist led care group. However, the difference was not statistically significant (p>0.05). The mean QoL score of each key domain of QoL was higher in nurse led care group when compared to oncologist led care group. Overall, significant improvement in quality of life was observed in individuals underwent in nurse led care group than oncologist led care group.
The results of this preliminary study showed that NLC results in better clinical outcome in terms of improvement in pain intensity, dyspnea intensity, symptom distress, constipation score, and QOL in comparison to oncologist led care among Chinese cancer patients. This study results can aid as a base for steering outsized clinical study to form the model of NLC among Chinese cancer patients.
肿瘤学中的 NLC 模式在中国尚未得到很好的建立,也没有研究评估 NLC 与肿瘤医生主导的护理(OLC)在癌症中国患者中的临床效果。因此,我们设计了一项试点研究,以评估 NLC 与 OLC 在中国癌症患者中的临床应用效果。
本试点、单中心、前瞻性研究旨在评估 NLC 与 OLC 在癌症中国患者中的临床效果。本研究纳入了在中国被诊断患有任何癌症的成年患者(年龄在 20 至 65 岁之间)。在筛选阶段,排除了患有 IV 期癌症或不愿书面同意参与本研究的患者。我们评估了每位入组患者的症状,任何癌症患者最常见的症状是疼痛、呼吸困难和便秘。此外,晚期癌症患者还会出现痛苦症状(由疼痛和呼吸困难引起)和生活质量低下。
共有 220 名在我院就诊的患者被纳入并分配到护士主导的护理组和肿瘤医生主导的护理组(每组 110 名患者)。记录了护士主导的护理组和肿瘤医生主导的护理组患者的疼痛强度、呼吸困难强度和便秘强度。与肿瘤医生主导的护理组相比,护士主导的护理组的疼痛强度、呼吸困难强度和便秘强度在数字评分量表上的数值较小。然而,差异无统计学意义(p>0.05)。护士主导的护理组在每个生活质量关键领域的平均 QoL 评分均高于肿瘤医生主导的护理组。总体而言,与肿瘤医生主导的护理组相比,在护士主导的护理组中,个体的生活质量得到了显著改善。
这项初步研究的结果表明,与肿瘤医生主导的护理相比,NLC 可改善疼痛强度、呼吸困难强度、症状痛苦、便秘评分和 QOL,从而带来更好的临床效果。这些研究结果可以为在中国癌症患者中建立 NLC 模式的大型临床试验提供基础。