Matthews Debora C, Brillant Martha G S, Jimoh Kudirat O, Singleton Winston, McLean-Veysey Pamela, Sketris Ingrid
Faculty of Dentistry (Matthews, Brilliant), Dalhousie University, Halifax, NS; private practice (Jimoh), Truro, NS; MetroHealth System (Singleton), Cleveland, Ohio; Nova Scotia Health Authority (McLean-Veysey); College of Pharmacy (Sketris), Dalhousie University, Halifax, NS
Faculty of Dentistry (Matthews, Brilliant), Dalhousie University, Halifax, NS; private practice (Jimoh), Truro, NS; MetroHealth System (Singleton), Cleveland, Ohio; Nova Scotia Health Authority (McLean-Veysey); College of Pharmacy (Sketris), Dalhousie University, Halifax, NS.
CMAJ Open. 2019 Aug 6;7(3):E497-E503. doi: 10.9778/cmajo.20190021. Print 2019 Jul-Sep.
Dentists are regular prescribers of opioid analgesic medications; however, there are few published data on their prescribing practices for children. The aim of this study was to assess opioid prescribing practices of dentists for pediatric patients.
We conducted a retrospective study (2011/12 to 2017/18) using administrative health data of opioid prescribing practices of dentists in Nova Scotia for children and adolescents (age < 18 yr). The main variables of interest were opioid "type" and "load" dentists prescribed (number of dispensed prescriptions/yr, days supplied/prescription and dosage/d per prescription in milligrams of morphine equivalents [MME]).
Dentists accounted for a mean of 18.3% (standard deviation 1.5%) of all opioid prescribers for the pediatric population annually but were responsible for 59.9% of all opioid prescriptions and 48.6% of total MME dispensed during the 7-year study period. Oral and maxillofacial surgeons were responsible for 80.7% of all dental-related opioids dispensed. Codeine was most frequently prescribed (78.6% of total MME), followed by oxycodone (11.1%). There were significant downward trends over the study period in the total amount of opioid analgesics dispensed ( = -0.903, < 0.01), primarily due to a reduction in the total amount of codeine dispensed and number of days supplied per prescription ( = -0.837, < 0.05). Few opioids were dispensed to children less than 12 years.
Dentists in Nova Scotia reduced prescriptions of opioids in the pediatric population between 2011/12 and 2017/18, which may indicate that current opioid prescribing principles are influencing dentists' prescribing habits. Nonetheless, patients and parents should receive appropriate counselling as to the proper use, risks, storage and potential for misuse of opioids when prescribed.
牙医是阿片类镇痛药物的常规开方者;然而,关于他们为儿童开方的做法,发表的数据很少。本研究的目的是评估牙医为儿科患者开阿片类药物的做法。
我们利用新斯科舍省牙医为儿童和青少年(年龄<18岁)开阿片类药物的行政健康数据进行了一项回顾性研究(2011/12至2017/18)。主要关注变量是牙医开出的阿片类药物“类型”和“剂量”(每年配发的处方数量、每张处方的供应天数以及每张处方以毫克吗啡当量[MME]计的每日剂量)。
在为期7年的研究期间,牙医每年平均占儿科人群所有阿片类药物开方者的18.3%(标准差1.5%),但开出了所有阿片类药物处方的59.9%以及配发的总MME的48.6%。口腔颌面外科医生开出了所有与牙科相关阿片类药物的80.7%。最常开出的是可待因(占总MME的78.6%),其次是羟考酮(11.1%)。在研究期间,阿片类镇痛药的总配发量呈显著下降趋势(=-0.903,<0.01),主要原因是可待因的总配发量和每张处方的供应天数减少(=-0.837,<0.05)。很少有阿片类药物配发给12岁以下儿童。
2011/12至2017/18年间,新斯科舍省的牙医减少了儿科人群阿片类药物的处方量,这可能表明当前的阿片类药物开方原则正在影响牙医的开方习惯。尽管如此,在开阿片类药物处方时,患者和家长应接受关于阿片类药物正确使用、风险、储存及滥用可能性的适当咨询。